Andrew J. Wiemer, Ph.D.

Affiliations: 
2008 University of Iowa, Iowa City, IA 
 2012- University of Connecticut, Storrs, CT, United States 
Area:
Biochemistry
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"Andrew J. Wiemer"
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DOI: 10.1021/acsmedchemlett.7b00245

Parents

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Raymond J. Hohl grad student 2008 University of Iowa
 (Inhibition of geranylgeranyl diphosphate synthase by isoprenoid bisphosphonates.)
Anna Huttenlocher post-doc UW Madison
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Publications

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Haney SL, Varney ML, Safranek HR, et al. (2018) Tropolone-induced effects on the unfolded protein response pathway and apoptosis in multiple myeloma cells are dependent on iron. Leukemia Research. 77: 17-27
Lentini N, Foust BJ, Hsiao CC, et al. (2018) Phosphonamidate prodrugs of a butyrophilin ligand display plasma stability and potent Vγ9Vδ2 T cell stimulation. Journal of Medicinal Chemistry
Haney SL, Allen C, Varney ML, et al. (2017) Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells. Oncotarget. 8: 76085-76098
Foust BJ, Poe MM, Lentini NA, et al. (2017) Mixed Aryl Phosphonate Prodrugs of a Butyrophilin Ligand. Acs Medicinal Chemistry Letters. 8: 914-918
Haney SL, Allen C, Varney ML, et al. (2017) Novel tropolones induce the unfolded protein response pathway and apoptosis in multiple myeloma cells. Oncotarget
Shippy RR, Lin X, Agabiti SS, et al. (2017) Phosphinophosphonates and their tris-pivaloyloxymethyl prodrugs reveal a negatively cooperative butyrophilin activation mechanism. Journal of Medicinal Chemistry
Li J, Falcone ER, Holstein SA, et al. (2016) Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis. Pharmacological Research
Wiemer AJ, Shippy RR, Kilcollins AM, et al. (2015) Evaluation of a 7-methoxycoumarin-3-carboxylic acid ester derivative as a fluorescent, cell-cleavable, phosphonate protecting group. Chembiochem : a European Journal of Chemical Biology
Wiemer AJ, Wiemer DF. (2015) Prodrugs of phosphonates and phosphates: crossing the membrane barrier. Topics in Current Chemistry. 360: 115-60
Hsiao CHC, Lin X, Barney RJ, et al. (2015) Synthesis and Biological Evaluation of a Phosphonate Phosphoantigen Prodrug Phosphorus, Sulfur and Silicon and the Related Elements. 190: 751-753
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