Sheng F. Cai, Ph.D.

Affiliations: 
2011 Biology & Biomedical Sciences (Immunology) Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology
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"Sheng Cai"

Parents

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Timothy J. Ley grad student 2011 Washington University
 (Granzyme expression and function in effector and regulatory T cells.)
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Publications

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Cai SF, Cao X, Hassan A, et al. (2010) Granzyme B is not required for regulatory T cell-mediated suppression of graft-versus-host disease. Blood. 115: 1669-77
Cao X, Leonard K, Collins LI, et al. (2009) Interleukin 12 stimulates IFN-gamma-mediated inhibition of tumor-induced regulatory T-cell proliferation and enhances tumor clearance. Cancer Research. 69: 8700-9
Cai SF, Fehniger TA, Cao X, et al. (2009) Differential expression of granzyme B and C in murine cytotoxic lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 182: 6287-97
Cao X, Collins LI, Cai SF, et al. (2008) IL-12 Stimulates Interferon-Gamma Mediated Inhibition of Tumor-Induced Regulatory T Cell Proliferation and Enhances Tumor Clearance Blood. 112: 2558-2558
Cao X, Cai SF, Fehniger TA, et al. (2007) Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance. Immunity. 27: 635-46
Fehniger TA, Cai SF, Cao X, et al. (2007) Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs. Immunity. 26: 798-811
Cai SF, Fehniger TA, Dai X, et al. (2007) Differential Regulation of Granzyme B and C Expression in Murine Cytotoxic T and NK Cells. Blood. 110: 2291-2291
Fehniger TA, Cai SF, Cao X, et al. (2006) Murine NK Cells Require Activation-Dependent Expression of Granzyme B and Perforin To Become Potent Cytotoxic Effectors. Blood. 108: 920-920
Cao X, Cai SF, Fehniger TA, et al. (2006) Granzyme B Is Important for Treg-Mediated Suppression of NK-Dependent Tumor Clearance In Vivo. Blood. 108: 133-133
Cai SF, Kirby RJ, Howles PN, et al. (2000) Differentiation-dependent expression of the class B Type I scavenger receptor in intestinal cells Gastroenterology. 118: A661
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