Mei-Chih Liang, Ph.D.

2006 Boston University, Boston, MA, United States 
Molecular Biology, Cell Biology
"Mei-Chih Liang"


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Thomas D. Gilmore grad student 2006 Boston University
 (Derivatives of epoxyquinoid natural products that block activation of transcription factor NF -kappaB at multiple steps.)
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Pan CH, Chang YF, Lee MS, et al. (2016) Vorinostat enhances the cisplatin-mediated anticancer effects in small cell lung cancer cells. Bmc Cancer. 16: 857
Chung TW, Hung YT, Thikekar T, et al. (2015) Telescoped Synthesis of 2-Acyl-1-aryl-1,2-dihydroisoquinolines and Their Inhibition of the Transcription Factor NF-κB. Acs Combinatorial Science. 17: 442-51
Schoeberl B, Faber AC, Li D, et al. (2010) An ErbB3 antibody, MM-121, is active in cancers with ligand-dependent activation. Cancer Research. 70: 2485-94
Roccaro AM, Sacco A, Husu EN, et al. (2010) Dual targeting of the PI3K/Akt/mTOR pathway as an antitumor strategy in Waldenstrom macroglobulinemia. Blood. 115: 559-69
Li C, Pace EA, Liang M, et al. (2010) ChemInform Abstract: Total Synthesis of the NF-ϰB Inhibitor (-)-Cycloepoxydon (I): Utilization of Tartrate-Mediated Nucleophilic Epoxidation. Cheminform. 33: no-no
Faber AC, Li D, Song Y, et al. (2009) Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition. Proceedings of the National Academy of Sciences of the United States of America. 106: 19503-8
Liang MC, Bardhan S, Pace EA, et al. (2006) Inhibition of transcription factor NF-kappaB signaling proteins IKKbeta and p65 through specific cysteine residues by epoxyquinone A monomer: correlation with its anti-cancer cell growth activity. Biochemical Pharmacology. 71: 634-45
Liang MC, Bardhan S, Porco JA, et al. (2006) The synthetic epoxyquinoids jesterone dimer and epoxyquinone A monomer induce apoptosis and inhibit REL (human c-Rel) DNA binding in an IkappaBalpha-deficient diffuse large B-cell lymphoma cell line. Cancer Letters. 241: 69-78
Gilmore TD, Kalaitzidis D, Liang MC, et al. (2004) The c-Rel transcription factor and B-cell proliferation: a deal with the devil. Oncogene. 23: 2275-86
Liang MC, Bardhan S, Li C, et al. (2003) Jesterone dimer, a synthetic derivative of the fungal metabolite jesterone, blocks activation of transcription factor nuclear factor kappaB by inhibiting the inhibitor of kappaB kinase. Molecular Pharmacology. 64: 123-31
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