Gayathri Swaminathan, Ph.D.

Affiliations: 
2006 Temple University, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology
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"Gayathri Swaminathan"

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Alexander Y. Tsygankov grad student 2006 Temple University
 (Role of membrane association of c -CBL in c-CBL facilitated cytoskeletal effects in v-Abl-transformed fibroblasts.)
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Publications

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Swaminathan G, Cartwright CA. (2012) Rack1 promotes epithelial cell-cell adhesion by regulating E-cadherin endocytosis. Oncogene. 31: 376-89
Varghese B, Swaminathan G, Plotnikov A, et al. (2010) Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferation. Molecular Endocrinology (Baltimore, Md.). 24: 2356-65
Varghese B, Barriere H, Carbone CJ, et al. (2008) Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway. Molecular and Cellular Biology. 28: 5275-87
Swaminathan G, Varghese B, Thangavel C, et al. (2008) Prolactin stimulates ubiquitination, initial internalization, and degradation of its receptor via catalytic activation of Janus kinase 2. The Journal of Endocrinology. 196: R1-7
Swaminathan G, Varghese B, Fuchs SY. (2008) Regulation of prolactin receptor levels and activity in breast cancer. Journal of Mammary Gland Biology and Neoplasia. 13: 81-91
Kumar KG, Barriere H, Carbone CJ, et al. (2007) Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis. The Journal of Cell Biology. 179: 935-50
Swaminathan G, Feshchenko EA, Tsygankov AY. (2007) c-Cbl-facilitated cytoskeletal effects in v-Abl-transformed fibroblasts are regulated by membrane association of c-Cbl. Oncogene. 26: 4095-105
Swaminathan G, Tsygankov AY. (2006) The Cbl family proteins: ring leaders in regulation of cell signaling. Journal of Cellular Physiology. 209: 21-43
Feshchenko EA, Smirnova EV, Swaminathan G, et al. (2004) TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin. Oncogene. 23: 4690-706
Tsygankov AY, Teckchandani AM, Feshchenko EA, et al. (2001) Beyond the RING: CBL proteins as multivalent adapters. Oncogene. 20: 6382-402
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