Anne S. Hutchins, Ph.D.

2003 University of Pennsylvania, Philadelphia, PA, United States 
Cell Biology, Genetics, Molecular Biology
"Anne Hutchins"


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Steven L. Reiner grad student 2003 Penn
 (Helper T cell differentiation as a model for chromatin-based gene silencing.)
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Martins GA, Hutchins AS, Reiner SL. (2005) Transcriptional activators of helper T cell fate are required for establishment but not maintenance of signature cytokine expression. Journal of Immunology (Baltimore, Md. : 1950). 175: 5981-5
Hutchins AS, Artis D, Hendrich BD, et al. (2005) Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity. Journal of Immunology (Baltimore, Md. : 1950). 175: 5606-10
Pearce EL, Mullen AC, Martins GA, et al. (2003) Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science (New York, N.Y.). 302: 1041-3
Reiner SL, Mullen AC, Hutchins AS, et al. (2003) Helper T cell differentiation and the problem of cellular inheritance. Immunologic Research. 27: 463-8
Hutchins AS, Mullen AC, Lee HW, et al. (2002) Gene silencing quantitatively controls the function of a developmental trans-activator. Molecular Cell. 10: 81-91
Mullen AC, Hutchins AS, High FA, et al. (2002) Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction. Nature Immunology. 3: 652-8
Mullen AC, Hutchins AS, Villarino AV, et al. (2001) Cell cycle controlling the silencing and functioning of mammalian activators. Current Biology : Cb. 11: 1695-9
Doyle AM, Mullen AC, Villarino AV, et al. (2001) Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells. The Journal of Experimental Medicine. 194: 893-902
Mullen AC, High FA, Hutchins AS, et al. (2001) Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science (New York, N.Y.). 292: 1907-10
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