Andrew M. Intlekofer, Ph.D.

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology, Molecular Biology, General Biology
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"Andrew Intlekofer"

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Steven L. Reiner grad student 2007 Penn
 (The role of T-bet and eomesodermin in effector and memory CD8+ T cell differentiation.)
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Publications

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Holling GA, Chavel CA, Sharda AP, et al. (2024) CD8+ T cell metabolic flexibility elicited by CD28-ARS2 axis-driven alternative splicing of PKM supports antitumor immunity. Cellular & Molecular Immunology
Schrecker C, Intlekofer AM. (2021) T cells critically depend on pyruvate oxidation. Cell Metabolism. 33: 1719-1720
Campbell C, Marchildon F, Michaels AJ, et al. (2020) FXR mediates T cell-intrinsic responses to reduced feeding during infection. Proceedings of the National Academy of Sciences of the United States of America
Stahl M, Epstein-Peterson ZD, Intlekofer AM. (2020) Oncogenic Mechanisms and Therapeutic Targeting of Metabolism in Leukemia and Lymphoma. Cold Spring Harbor Perspectives in Medicine
Madala HR, Helenius IT, Zhou W, et al. (2020) Nitrogen trapping as a therapeutic strategy in tumors with mitochondrial dysfunction. Cancer Research
Kingsley MC, Xie HM, Chen BR, et al. (2020) Specific patterns of H3K79 methylation influence genetic interaction of oncogenes in AML. Blood Advances. 4: 3109-3122
Intlekofer AM, Joffe E, Batlevi CL, et al. (2018) Integrated DNA/RNA targeted genomic profiling of diffuse large B-cell lymphoma using a clinical assay. Blood Cancer Journal. 8: 60
McKenney AS, Lau AN, Somasundara AVH, et al. (2018) JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition. The Journal of Clinical Investigation
Pavlova NN, Hui S, Ghergurovich JM, et al. (2018) As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid. Cell Metabolism
Shih AH, Meydan C, Shank K, et al. (2017) Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia. Cancer Discovery
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