Eugene Khandros, Ph.D.
Affiliations: | 2012 | Cell and Molecular Biology | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Cell Biology, Molecular Biology, BiochemistryGoogle:
"Eugene Khandros"Parents
Sign in to add mentor| Mitchell J. Weiss | grad student | 2012 | Penn | |
| (Protein quality control in hemoglobin synthesis and beta-thalassemia.) | ||||
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Publications
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| Huang P, Peslak SA, Ren R, et al. (2022) HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription. Nature Genetics |
| Qin K, Huang P, Feng R, et al. (2022) Publisher Correction: Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Nature Genetics |
| Wakabayashi A, Kihiu M, Sharma M, et al. (2022) Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression. Blood Advances |
| Qin K, Huang P, Feng R, et al. (2022) Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Nature Genetics |
| Peslak SA, Khandros E, Huang P, et al. (2020) HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation. Blood Advances. 4: 4560-4572 |
| Huang P, Peslak SA, Lan X, et al. (2020) HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression. Blood |
| Khandros E, Huang P, Peslak SA, et al. (2020) Understanding Heterogeneity of Fetal Hemoglobin Induction through Comparative Analysis of F- and A-erythroblasts. Blood |
| Lechauve C, Keith J, Khandros E, et al. (2019) The autophagy-activating kinase ULK1 mediates clearance of free α-globin in β-thalassemia. Science Translational Medicine. 11 |
| Chonat S, Risinger M, Sakthivel H, et al. (2019) The Spectrum of -Associated Hereditary Spherocytosis. Frontiers in Physiology. 10: 815 |
| Lan X, Khandros E, Huang P, et al. (2019) The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells. Blood Advances. 3: 1586-1597 |