Alexandra M. Ortiz, Ph.D.

Affiliations: 
2012 Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology
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"Alexandra Ortiz"

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Guido Silvestri grad student 2012 Penn
 (Contributions of CD4+ T-cells to pathogenic and nonpathogenic SIV disease progression.)
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Publications

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Ortiz AM, Castello Casta F, Rahmberg A, et al. (2023) 2-Hydroxypropyl-β-Cyclodextrin Treatment Induces Modest Immune Activation in Healthy Rhesus Macaques. Journal of Virology. e0060023
Simpson J, Starke CE, Ortiz AM, et al. (2022) Multiple modes of antigen exposure induce clonotypically diverse epitope-specific CD8+ T cells across multiple tissues in nonhuman primates. Plos Pathogens. 18: e1010611
Ortiz AM, Simpson J, Langner CA, et al. (2022) Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques. Scientific Reports. 12: 7491
Bochart RM, Busman-Sahay K, Bondoc S, et al. (2021) Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques. Plos Pathogens. 17: e1009565
Flynn JK, Langner CA, Karmele EP, et al. (2021) Luminal microvesicles uniquely influence translocating bacteria after SIV infection. Mucosal Immunology
Sortino O, Phanuphak N, Schuetz A, et al. (2020) Impact of Acute HIV Infection and Early Antiretroviral Therapy on the Human Gut Microbiome. Open Forum Infectious Diseases. 7: ofz367
Vinton CL, Magaziner SJ, Dowd KA, et al. (2019) Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance. Mbio. 10
Starke CE, Vinton CL, Ladell K, et al. (2019) SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues. The Journal of Clinical Investigation
Ortiz AM, Flynn JK, DiNapoli SR, et al. (2019) Antiretroviral therapy administration in healthy rhesus macaques is associated with transient shifts in intestinal bacterial diversity and modest immunological perturbations. Journal of Virology
Lai S, Starke CE, Flynn JK, et al. (2019) SIV infects functionally polarized memory CD4 T cells equivalently . Journal of Virology
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