Charles W. Pemble, Ph.D.
Affiliations: | 2008 | Wake Forest University, Winston-Salem, NC, United States |
Area:
BiochemistryGoogle:
"Charles Pemble"Parents
Sign in to add mentor| W Todd Lowther | grad student | 2008 | Wake Forest | |
| (Structural and functional analysis of the thioesterase domain of human fatty acid synthase.) | ||||
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Publications
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| Ritchie MK, Johnson LC, Clodfelter JE, et al. (2015) Crystal Structure and Substrate Specificity of Human Thioesterase 2: Insights into the Molecular Basis for the Modulation of Fatty Acid Synthase. The Journal of Biological Chemistry |
| Pemble CW, Mehta PK, Mehra S, et al. (2010) Crystal structure of the 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase•dihydropteroate synthase bifunctional enzyme from Francisella tularensis. Plos One. 5: e14165 |
| Kridel SJ, Lowther WT, Pemble CW. (2007) Fatty acid synthase inhibitors: new directions for oncology. Expert Opinion On Investigational Drugs. 16: 1817-29 |
| Pemble CW, Johnson LC, Kridel SJ, et al. (2007) Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat. Nature Structural & Molecular Biology. 14: 704-9 |