Bradley T. Scroggins, Ph.D.
Affiliations: | 2002 | Oklahoma State University, Stillwater, OK, United States |
Area:
BiochemistryGoogle:
"Bradley Scroggins"Parents
Sign in to add mentor| Robert L. Matts | grad student | 2002 | Oklahoma State University | |
| (The role of heat shock proteins in p56(lck) kinase folding and function.) | ||||
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Publications
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| Sourbier C, Liao PJ, Ricketts CJ, et al. (2018) Targeting loss of the Hippo signaling pathway in-deficient papillary kidney cancers. Oncotarget. 9: 10723-10733 |
| Chung EJ, McKay-Corkum G, Chung S, et al. (2015) Truncated Plasminogen Activator Inhibitor-1 Protein Protects From Pulmonary Fibrosis Mediated by Irradiation in a Murine Model. International Journal of Radiation Oncology, Biology, Physics |
| Prince TL, Kijima T, Tatokoro M, et al. (2015) Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants. Plos One. 10: e0141786 |
| Sourbier C, Scroggins BT, Mannes PZ, et al. (2015) Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent. Oncotarget. 6: 29963-74 |
| Beebe K, Mollapour M, Scroggins B, et al. (2013) Posttranslational modification and conformational state of heat shock protein 90 differentially affect binding of chemically diverse small molecule inhibitors. Oncotarget. 4: 1065-74 |
| Sourbier C, Scroggins BT, Ratnayake R, et al. (2013) Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality. Cancer Cell. 23: 228-37 |
| Solier S, Kohn KW, Scroggins B, et al. (2012) Heat shock protein 90α (HSP90α), a substrate and chaperone of DNA-PK necessary for the apoptotic response Proceedings of the National Academy of Sciences of the United States of America. 109: 12866-12872 |
| Xu W, Mollapour M, Prodromou C, et al. (2012) Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine. Molecular Cell. 47: 434-43 |
| Sun L, Prince T, Manjarrez JR, et al. (2012) Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins. Biochimica Et Biophysica Acta. 1823: 1092-101 |
| Mollapour M, Tsutsumi S, Donnelly AC, et al. (2010) Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function. Molecular Cell. 37: 333-43 |