Robert H. Vonderheide

Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Cell Biology, Immunology, Oncology
"Robert Vonderheide"


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Simon V. Hunt grad student 1987-1990 Sir William Dunn School of Pathology University of Oxford (Neurotree)
 (Since 2017, Director Abramson Cancer Center, John H. Glick Abramson Cancer Center Professor, UPenn.)


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Erica L. Carpenter grad student 2009 Penn
Lauren J. Bayne grad student 2012 Penn
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O'Hara MH, O'Reilly EM, Varadhachary G, et al. (2021) CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study. The Lancet. Oncology. 22: 118-131
Reiss KA, Wattenberg MM, Damjanov N, et al. (2020) A Pilot Study of Galunisertib Plus Stereotactic Body Radiotherapy in Patients with Advanced Hepatocellular Carcinoma. Molecular Cancer Therapeutics
Lin JH, Huffman AP, Wattenberg MM, et al. (2020) Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis. The Journal of Experimental Medicine. 217
Aiello NM, Bajor DL, Norgard RJ, et al. (2016) Metastatic progression is associated with dynamic changes in the local microenvironment. Nature Communications. 7: 12819
Bronte V, Brandau S, Chen SH, et al. (2016) Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards. Nature Communications. 7: 12150
Byrne KT, Vonderheide RH. (2016) CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer. Cell Reports
Byrne KT, Leisenring NH, Bajor DL, et al. (2016) CSF-1R-Dependent Lethal Hepatotoxicity When Agonistic CD40 Antibody Is Given before but Not after Chemotherapy. Journal of Immunology (Baltimore, Md. : 1950)
Hexner EO, Luger SM, Reshef R, et al. (2016) Infusion of CD3/CD28 co-stimulated umbilical cord blood T cells at the time of single umbilical cord blood transplantation may enhance engraftment. American Journal of Hematology
Lee KE, Spata M, Bayne LJ, et al. (2015) Hif1α deletion reveals pro-neoplastic function of B cells in pancreatic neoplasia. Cancer Discovery
Vonderheide RH. (2015) CD47 blockade as another immune checkpoint therapy for cancer. Nature Medicine. 21: 1122-3
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