Robert H. Vonderheide

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Immunology, Oncology
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"Robert Vonderheide"

Parents

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Simon V. Hunt grad student 1987-1990 Sir William Dunn School of Pathology University of Oxford (Neurotree)
 (Since 2017, Director Abramson Cancer Center, John H. Glick Abramson Cancer Center Professor, UPenn.)

Children

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Erica L. Carpenter grad student 2009 Penn
Lauren J. Bayne grad student 2012 Penn
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Publications

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Kim IK, Diamond MS, Yuan S, et al. (2024) Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma. Nature Communications. 15: 1532
Blise KE, Sivagnanam S, Betts CB, et al. (2023) Machine learning links T cell function and spatial localization to neoadjuvant immunotherapy and clinical outcome in pancreatic cancer. Biorxiv : the Preprint Server For Biology
Cheng NC, Vonderheide RH. (2023) Immune vulnerabilities of mutant KRAS in pancreatic cancer. Trends in Cancer
Kim IK, Diamond M, Yuan S, et al. (2023) Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy. Research Square
Kim R, Taylor D, Vonderheide RH, et al. (2023) Ferroptosis of immune cells in the tumor microenvironment. Trends in Pharmacological Sciences
Schratz KE, Flasch DA, Atik CC, et al. (2023) T cell immune deficiency rather than chromosome instability predisposes patients with short telomere syndromes to squamous cancers. Cancer Cell. 41: 807-817.e6
Kemp SB, Cheng N, Markosyan N, et al. (2022) Efficacy of a small molecule inhibitor of KrasG12D in immunocompetent models of pancreatic cancer. Cancer Discovery
Padrón LJ, Maurer DM, O'Hara MH, et al. (2022) Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial. Nature Medicine
Bear AS, Blanchard T, Cesare J, et al. (2021) Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting. Nature Communications. 12: 4365
Diamond MS, Lin JH, Vonderheide RH. (2021) Site-dependent immune escape of highly antigenic tumors without immunoediting. Cancer Immunology Research
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