Rebecca C. Schugar, Ph.D.

Affiliations: 
2014 Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Molecular Biology, Cell Biology, Pathology
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"Rebecca Schugar"

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Peter A. Crawford grad student 2014 Washington University
 (Cardiomyocyte-Specific Deficiency of Ketone Body Metabolism Promotes Accelerated Pathological Remodeling.)
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Publications

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Schugar RC, Gliniak CM, Osborn LJ, et al. (2022) Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms. Elife. 11
Zhou H, Wang H, Yu M, et al. (2020) IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes. Nature Immunology
Shih DM, Zhu W, Schugar RC, et al. (2019) Genetic Deficiency of Flavin-Containing Monooxygenase-3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119312592
Lieber AD, Beier UH, Xiao H, et al. (2018) Loss of HDAC6 alters gut microbiota and worsens obesity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701586R
Ding L, Zhang L, Biswas S, et al. (2017) Akt3 inhibits adipogenesis and protects from diet-induced obesity via WNK1/SGK1 signaling Jci Insight. 2
Schugar RC, Willard B, Wang Z, et al. (2017) Postprandial gut microbiota-driven choline metabolism links dietary cues to adipose tissue dysfunction. Adipocyte. 1-8
Lord CC, Ferguson D, Thomas G, et al. (2016) Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation. Cell Reports
Schugar RC, Brown JM. (2015) Emerging roles of flavin monooxygenase 3 in cholesterol metabolism and atherosclerosis. Current Opinion in Lipidology. 26: 426-31
Warrier M, Shih DM, Burrows AC, et al. (2015) The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance. Cell Reports
Schugar RC, Moll AR, André d'Avignon D, et al. (2014) Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling. Molecular Metabolism. 3: 754-69
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