John A. Pezza, Ph.D.

Affiliations: 
2006 Boston University, Boston, MA, United States 
Area:
Biochemistry, Molecular Biology
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"John Pezza"

Parents

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Dean Tolan grad student 2006 Boston University
 (Interactions among isozyme-specific residues in fructose -1,6 -bisphosphate aldolase.)
Tricia R. Serio post-doc U Mass Amherst
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Publications

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Pezza JA, Villali J, Sindi SS, et al. (2014) Amyloid-associated activity contributes to the severity and toxicity of a prion phenotype. Nature Communications. 5: 4384
DiSalvo S, Derdowski A, Pezza JA, et al. (2011) Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation. Nature Structural & Molecular Biology. 18: 486-92
Pezza JA, Langseth SX, Raupp Yamamoto R, et al. (2009) The NatA acetyltransferase couples Sup35 prion complexes to the [PSI+] phenotype. Molecular Biology of the Cell. 20: 1068-80
Pezza JA, Serio TR. (2007) Prion propagation: the role of protein dynamics. Prion. 1: 36-43
Pezza JA, Stopa JD, Brunyak EM, et al. (2007) Thermodynamic analysis shows conformational coupling and dynamics confer substrate specificity in fructose-1,6-bisphosphate aldolase Biochemistry. 46: 13010-13018
Arakaki TL, Pezza JA, Cronin MA, et al. (2004) Structure of human brain fructose 1,6-(bis)phosphate aldolase: linking isozyme structure with function. Protein Science : a Publication of the Protein Society. 13: 3077-84
Pezza JA, Allen KN, Tolan DR. (2004) Intein-mediated purification of a recombinantly expressed peptide Chemical Communications. 10: 2412-2413
Pezza JA, Choi KH, Berardini TZ, et al. (2003) Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose-1,6-bisphosphate aldolase Journal of Biological Chemistry. 278: 17307-17313
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