Arash Shahangian, Ph.D.

Affiliations: 
2008 University of California, Los Angeles, Los Angeles, CA 
Area:
Microbiology Biology, Immunology, Molecular Biology
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"Arash Shahangian"

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Genhong Cheng grad student 2008 UCLA
 (Influenza-induced type I interferons sensitize hosts to secondary pneumococcal pneumonia.)
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Publications

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Ding X, Sanchez DJ, Shahangian A, et al. (2012) Cascade search for HSV-1 combinatorial drugs with high antiviral efficacy and low toxicity. International Journal of Nanomedicine. 7: 2281-92
Shahangian A, Chow EK, Tian X, et al. (2009) Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice. The Journal of Clinical Investigation. 119: 1910-20
Miyahira AK, Shahangian A, Hwang S, et al. (2009) TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections. Journal of Immunology (Baltimore, Md. : 1950). 182: 2248-57
Cheng LS, Hwang S, Huang TH, et al. (2008) Antibody-fused interferons as an effective approach to enhance target specificity and antiviral efficacy of type I interferons. Cell Research. 18: 1230-2
Wong PK, Yu F, Shahangian A, et al. (2008) Closed-loop control of cellular functions using combinatory drugs guided by a stochastic search algorithm. Proceedings of the National Academy of Sciences of the United States of America. 105: 5105-10
Sanchez DJ, Miranda D, Arumugaswami V, et al. (2008) A repetitive region of gammaherpesvirus genomic DNA is a ligand for induction of type I interferon. Journal of Virology. 82: 2208-17
Chow EK, Castrillo A, Shahangian A, et al. (2006) A role for IRF3-dependent RXRalpha repression in hepatotoxicity associated with viral infections. The Journal of Experimental Medicine. 203: 2589-602
Saha SK, Pietras EM, He JQ, et al. (2006) Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif. The Embo Journal. 25: 3257-63
Miller LS, O'Connell RM, Gutierrez MA, et al. (2006) MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus. Immunity. 24: 79-91
Oganesyan G, Saha SK, Guo B, et al. (2006) Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature. 439: 208-11
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