Amy M. Lyndaker, Ph.D.

2009 Cornell University, Ithaca, NY, United States 
Molecular Biology, Genetics, Biochemistry
"Amy Lyndaker"


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Eric Alani grad student 2009 Cornell
 (Roles for the Rad1-Rad10-Slx4, Msh2-Msh6, and Sgs1 DNA repair factors in ensuring the efficiency and fidelity of homologous recombination in Saccharomyces cerevisiae.)
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Pereira C, Arroyo-Martinez GA, Guo MZ, et al. (2022) Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis. Elife. 11
Lyndaker AM, Pierpont TM, Loehr AR, et al. (2021) A Genetically Engineered Mouse Model of Malignant Testicular Germ Cell Tumors. Methods in Molecular Biology (Clifton, N.J.). 2195: 147-165
Loehr A, Pierpont T, Lyndaker A, et al. (2019) DNA damage response mechanisms in the origins and therapeutic sensitivity of testicular germ cell tumours European Urology Supplements. 18: 13
Pierpont TM, Lyndaker AM, Anderson CM, et al. (2017) Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer. Cell Reports. 21: 1896-1909
Chakraborty U, George CM, Lyndaker AM, et al. (2015) A Delicate Balance Between Repair and Replication Factors Regulates Recombination Between Divergent DNA Sequences in Saccharomyces cerevisiae. Genetics
Lim PX, Patel DR, Poisson KE, et al. (2015) Genome Protection by the 9-1-1 Complex Subunit HUS1 Requires Clamp Formation, DNA Contacts, and ATR Signaling-independent Effector Functions. The Journal of Biological Chemistry. 290: 14826-40
Lyndaker AM, Vasileva A, Wolgemuth DJ, et al. (2013) Clamping down on mammalian meiosis. Cell Cycle (Georgetown, Tex.). 12: 3135-45
Lyndaker AM, Lim PX, Mleczko JM, et al. (2013) Conditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenance. Plos Genetics. 9: e1003320
Balmus G, Zhu M, Mukherjee S, et al. (2012) Disease severity in a mouse model of ataxia telangiectasia is modulated by the DNA damage checkpoint gene Hus1. Human Molecular Genetics. 21: 3408-20
George CM, Lyndaker AM, Alani E. (2011) The DNA damage checkpoint allows recombination between divergent DNA sequences in budding yeast. Dna Repair. 10: 1086-94
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