Edwin Haghnazari, Ph.D.

Affiliations: 
2004 University of California, Davis, Davis, CA 
Area:
Genetics, Microbiology Biology
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"Edwin Haghnazari"

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Wolf-Dietrich Heyer grad student 2004 UC Davis
 (Regulation of homologous recombinational DNA repair by DNA damage and replication block checkpoints in Saccharomyces cerevisiae.)
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Publications

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Janke R, Herzberg K, Rolfsmeier M, et al. (2010) A truncated DNA-damage-signaling response is activated after DSB formation in the G1 phase of Saccharomyces cerevisiae. Nucleic Acids Research. 38: 2302-13
Navas T, Zhou L, Estes M, et al. (2008) Inhibition of p38alpha MAPK disrupts the pathological loop of proinflammatory factor production in the myelodysplastic syndrome bone marrow microenvironment. Leukemia & Lymphoma. 49: 1963-75
Herzberg K, Bashkirov VI, Rolfsmeier M, et al. (2006) Phosphorylation of Rad55 on serines 2, 8, and 14 is required for efficient homologous recombination in the recovery of stalled replication forks. Molecular and Cellular Biology. 26: 8396-409
Navas TA, Mohindru M, Estes M, et al. (2006) Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors. Blood. 108: 4170-7
Bashkirov VI, Herzberg K, Haghnazari E, et al. (2006) DNA damage-induced phosphorylation of Rad55 protein as a sentinel for DNA damage checkpoint activation in S. cerevisiae. Methods in Enzymology. 409: 166-82
Navas TA, Nguyen AN, Hideshima T, et al. (2006) Inhibition of p38alpha MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-X(L), Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo. Leukemia. 20: 1017-27
Nguyen AN, Stebbins EG, Henson M, et al. (2006) Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation. Experimental Cell Research. 312: 1909-23
Haghnazari E, Heyer WD. (2004) The DNA damage checkpoint pathways exert multiple controls on the efficiency and outcome of the repair of a double-stranded DNA gap. Nucleic Acids Research. 32: 4257-68
Haghnazari E, Heyer WD. (2004) The Hog1 MAP kinase pathway and the Mec1 DNA damage checkpoint pathway independently control the cellular responses to hydrogen peroxide. Dna Repair. 3: 769-76
Bashkirov VI, Bashkirova EV, Haghnazari E, et al. (2003) Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase. Molecular and Cellular Biology. 23: 1441-52
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