Marielle E. Yohe, Ph.D.

Affiliations: 
2007 Pharmacology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Medical Biophysics, Pharmacology
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"Marielle Yohe"

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John E. Sondek grad student 2007 UNC Chapel Hill
 (Regulation of the transforming immortalized mammary protein and its homologs by auto-inhibition and tyrosine phosphorylation.)
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Publications

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Rosenberg EM, Jian X, Soubias O, et al. (2023) The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins. The Journal of Biological Chemistry. 102992
Soubias O, Pant S, Heinrich F, et al. (2020) Membrane surface recognition by the ASAP1 PH domain and consequences for interactions with the small GTPase Arf1. Science Advances. 6
Liu Z, Zhang X, Lei H, et al. (2020) CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG. Nature Communications. 11: 911
Yohe ME, Gryder BE, Chou H, et al. (2020) Abstract B17: MEK inhibition induces myogenic differentiation in RAS-driven rhabdomyosarcoma Molecular Cancer Research. 18
Yeung C, Gibson AE, Issaq SH, et al. (2020) Abstract PR08: Lactate dehydrogenase A is a pharmacologically tractable EWS-FLI1 transcriptional target that regulates the glycolytic dependence of Ewing sarcoma Cancer Research. 80
Liu Z, Zhang X, Lei H, et al. (2020) Abstract B42: Mutant RAS represses CASZ1, a novel regulator of MYOD and MYOG, to inhibit embryonal rhabdomyosarcoma differentiation Cancer Research. 80
Hebron KE, Feehan-Nelson O, Jian X, et al. (2020) Abstract B32: ASAP1 regulates differentiation in myoblasts and PAX-FOXO1 fusion-negative rhabdomyosarcoma Cancer Research. 80
Cheuk A, Shivaprasad N, Schneider D, et al. (2020) Abstract A08: Development of FGFR4-specific chimeric antibody receptor (CAR) T cell and bispecific T cell engager (BiTE) for rhabdomyosarcoma (RMS) immunotherapy Cancer Research. 80
Roy NS, Jian X, Soubias O, et al. (2019) Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate. The Journal of Biological Chemistry
Yeung C, Gibson AE, Issaq SH, et al. (2019) Targeting glycolysis through inhibition of lactate dehydrogenase impairs tumor growth in preclinical models of Ewing sarcoma. Cancer Research
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