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Gregory D. Rak, Ph.D.

Affiliations: 
2011 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Immunology
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"Gregory Rak"
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Jordan S. Orange grad student 2011 Penn
 (Distribution of actin and access of lytic granules at the natural killer cell immunological synapse.)

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Rak GD, Osborne LC, Siracusa MC, et al. (2016) IL-33-Dependent Group 2 Innate Lymphoid Cells Promote Cutaneous Wound Healing. The Journal of Investigative Dermatology. 136: 487-96
Giacomin PR, Moy RH, Noti M, et al. (2015) Epithelial-intrinsic IKKα expression regulates group 3 innate lymphoid cell responses and antibacterial immunity. The Journal of Experimental Medicine
May RM, Okumura M, Hsu CJ, et al. (2013) Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function. Blood. 121: 3135-46
Sanborn KB, Mace EM, Rak GD, et al. (2011) Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity. Blood. 118: 5862-71
Rak GD, Mace EM, Banerjee PP, et al. (2011) Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse. Plos Biology. 9: e1001151
Orange JS, Roy-Ghanta S, Mace EM, et al. (2011) IL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function. The Journal of Clinical Investigation. 121: 1535-48
Sanborn KB, Rak GD, Mentlik AN, et al. (2010) Analysis of the NK cell immunological synapse. Methods in Molecular Biology (Clifton, N.J.). 612: 127-48
Sanborn KB, Rak GD, Maru SY, et al. (2009) Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse. Journal of Immunology (Baltimore, Md. : 1950). 182: 6969-84
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