Christopher R. Vakoc, Ph.D.

Affiliations: 
2008- Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 
Area:
Molecular Biology
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"Christopher Vakoc"

Parents

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Gerd A. Blobel grad student 2006 Penn
 (Histone lysine methylation and chromatin loop formation associated with transcription activation.)
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Publications

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Gao Y, Vakoc CR. (2024) Therapeutic index of targeting select chromatin complexes in human cancer patients. Current Opinion in Genetics & Development. 85: 102162
He T, Xiao L, Qiao Y, et al. (2024) Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies. Biorxiv : the Preprint Server For Biology
Duplaquet L, So K, Ying AW, et al. (2024) Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer. Biorxiv : the Preprint Server For Biology
Alpsoy A, Wu XS, Pal S, et al. (2024) IκBζ is a dual-use coactivator of NF-κB and POU transcription factors. Molecular Cell
Xu J, Roe JS, Lee E, et al. (2023) Engrailed-1 Promotes Pancreatic Cancer Metastasis. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2308537
Pomella S, Cassandri M, D'Archivio L, et al. (2023) MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57 targeting. Nature Communications. 14: 8373
Maia-Silva D, Schier AC, Skopelitis D, et al. (2023) Marker-based CRISPR screening reveals a MED12-p63 interaction that activates basal identity in pancreatic ductal adenocarcinoma. Biorxiv : the Preprint Server For Biology
Sroka MW, Skopelitis D, Vermunt MW, et al. (2023) Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303859120
Li BE, Li GY, Cai W, et al. (2023) In vivo CRISPR/Cas9 Screening Identifies Pbrm1 as a Regulator of Mouse Myeloid Leukemia Development. Blood Advances
Gao Y, He XY, Wu XS, et al. (2023) ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation. Nature Cell Biology
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