Trevor L. Hoffman, Ph.D.

Affiliations: 
2001 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Microbiology Biology, Cell Biology
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"Trevor Hoffman"

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Robert W. Doms grad student 2001 Penn
 (Structure-function studies of HIV-1 envelope protein.)
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Publications

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Demarest JF, Jack N, Cleghorn FR, et al. (2001) Immunologic and virologic analyses of an acutely HIV type 1-infected patient with extremely rapid disease progression. Aids Research and Human Retroviruses. 17: 1333-44
Edwards TG, Hoffman TL, Baribaud F, et al. (2001) Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein. Journal of Virology. 75: 5230-9
Hoffman TL, Canziani G, Jia L, et al. (2000) A biosensor assay for studying ligand-membrane receptor interactions: binding of antibodies and HIV-1 Env to chemokine receptors. Proceedings of the National Academy of Sciences of the United States of America. 97: 11215-20
Pierson T, Hoffman TL, Blankson J, et al. (2000) Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1. Journal of Virology. 74: 7824-33
LaBranche CC, Hoffman TL, Romano J, et al. (1999) Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity. Journal of Virology. 73: 10310-9
Pritsker M, Rucker J, Hoffman TL, et al. (1999) Effect of nonpolar substitutions of the conserved Phe11 in the fusion peptide of HIV-1 gp41 on its function, structure, and organization in membranes. Biochemistry. 38: 11359-71
Liu ZQ, Muhkerjee S, Sahni M, et al. (1999) Derivation and biological characterization of a molecular clone of SHIV(KU-2) that causes AIDS, neurological disease, and renal disease in rhesus macaques. Virology. 260: 295-307
Hoffman TL, LaBranche CC, Zhang W, et al. (1999) Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 6359-64
Hoffman TL, Doms RW. (1999) HIV-1 envelope determinants for cell tropism and chemokine receptor use. Molecular Membrane Biology. 16: 57-65
Martin V, Ronde P, Unett D, et al. (1999) Leukotriene binding, signaling, and analysis of HIV coreceptor function in mouse and human leukotriene B4 receptor-transfected cells. The Journal of Biological Chemistry. 274: 8597-603
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