Ryan R. Fortna, Ph.D.

Affiliations: 
2005 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology
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"Ryan Fortna"

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Robert W. Doms grad student 2005 Penn
 (Structural and functional studies on APH-1 and the gamma-secretase complex.)
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Publications

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Chiang PM, Fortna RR, Price DL, et al. (2012) Specific domains in anterior pharynx-defective 1 determine its intramembrane interactions with nicastrin and presenilin. Neurobiology of Aging. 33: 277-85
Morais VA, Brito C, Pijak DS, et al. (2006) N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53. Biochimica Et Biophysica Acta. 1762: 802-10
Crystal AS, Morais VA, Fortna RR, et al. (2004) Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation. Biochemistry. 43: 3555-63
Fortna RR, Crystal AS, Morais VA, et al. (2004) Membrane topology and nicastrin-enhanced endoproteolysis of APH-1, a component of the gamma-secretase complex. The Journal of Biological Chemistry. 279: 3685-93
Fortna RR, Schaller N, Morais VA, et al. (2004) P4-319 Assembly, trafficking, and activity of the gamma-secretase complex Neurobiology of Aging. 25: S566
Morais VA, Fortna RR, Crystal AS, et al. (2004) P4-282 Association and localization of nicastrin influences the activity of the G-secretase complex Neurobiology of Aging. 25: S555
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