Austin T. Thiel, Ph.D.
Affiliations: | 2012 | Cell and Molecular Biology | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Cell Biology, OncologyGoogle:
"Austin Thiel"Parents
Sign in to add mentor| Xianxin Hua | grad student | 2012 | Penn | |
| (The central role of menin and wild-type MLL in MLL-AF9-induced leukemia.) | ||||
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Publications
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| Thiel A, Yavanian G, Nastke MD, et al. (2015) Human embryonic stem cell-derived mesenchymal cells preserve kidney function and extend lifespan in NZB/W F1 mouse model of lupus nephritis. Scientific Reports. 5: 17685 |
| Matkar S, Thiel A, Hua X. (2013) Menin: a scaffold protein that controls gene expression and cell signaling. Trends in Biochemical Sciences. 38: 394-402 |
| Gurung B, Feng Z, Iwamoto DV, et al. (2013) Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome. Cancer Research. 73: 2650-8 |
| Thiel AT, Feng Z, Pant DK, et al. (2013) The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia. Haematologica. 98: 918-27 |
| Thiel AT, Huang J, Lei M, et al. (2012) Menin as a hub controlling mixed lineage leukemia Bioessays. 34: 771-780 |
| Thiel AT, Hua X. (2012) Abstract 4093: Investigating a role for menin and MLL-AF9 in suppressing C/EBPβ-mediated mixed lineage leukemia cell differentiation Cancer Research. 72: 4093-4093 |
| Thiel AT, Blessington P, Zou T, et al. (2010) MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele. Cancer Cell. 17: 148-59 |