Patrick Seale

Affiliations: 
Cell and Molecular Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology, Human Development
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"Patrick Seale"
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Publications

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Li J, Gui T, Yao L, et al. (2024) Synovium and infrapatellar fat pad share common mesenchymal progenitors and undergo coordinated changes in osteoarthritis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research
Tang S, Yao L, Ruan J, et al. (2024) Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology. Science Translational Medicine. 16: eadf4590
Jun S, Angueira AR, Fein EC, et al. (2023) Control of murine brown adipocyte development by GATA6. Developmental Cell
Holman CD, Sakers AP, Calhoun RP, et al. (2023) Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming. Biorxiv : the Preprint Server For Biology
Rahbani JF, Scholtes C, Lagarde DM, et al. (2022) ADRA1A-Gα signalling potentiates adipocyte thermogenesis through CKB and TNAP. Nature Metabolism
Sakers A, De Siqueira MK, Seale P, et al. (2022) Adipose-tissue plasticity in health and disease. Cell. 185: 419-446
Stefkovich M, Traynor S, Cheng L, et al. (2021) Dpp4+ interstitial progenitor cells contribute to basal and high fat diet-induced adipogenesis. Molecular Metabolism. 101357
Shao M, Zhang Q, Truong A, et al. (2021) ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes. Genes & Development
Choa R, Tohyama J, Wada S, et al. (2021) Thymic stromal lymphopoietin induces adipose loss through sebum hypersecretion. Science (New York, N.Y.). 373
Sostre-Colón J, Uehara K, Garcia Whitlock AE, et al. (2021) Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms. Cell Reports. 35: 109128
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