Zhong-Yin Zhang

Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Biochemistry, Analytical Chemistry, Molecular Biology
"Zhong-Yin Zhang"


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Jinpeng Sun grad student 2001-2006 (Neurotree)
Chad D. Walls grad student 2012 Indiana University
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Zhang RY, Yu ZH, Chen L, et al. (2020) Mechanistic insights explain the transforming potential of the T507K substitution in the protein tyrosine phosphatase SHP2. The Journal of Biological Chemistry
Dutta NK, He R, Pinn ML, et al. (2016) Mycobacterial Protein Tyrosine Phosphatases A and B Inhibitors Augment the Bactericidal Activity of the Standard Anti-tuberculosis Regimen Acs Infectious Diseases. 2: 231-239
He R, Yu ZH, Zhang RY, et al. (2015) Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. Acs Medicinal Chemistry Letters. 6: 782-6
He Y, Guo X, Yu ZH, et al. (2015) A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorganic & Medicinal Chemistry. 23: 2798-809
Dodd GT, Decherf S, Loh K, et al. (2015) Leptin and insulin act on POMC neurons to promote the browning of white fat. Cell. 160: 88-104
He R, Yu ZH, Zhang RY, et al. (2015) Cefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis Acs Medicinal Chemistry Letters. 6: 1231-1235
Paudyal MP, Wu L, Zhang ZY, et al. (2014) A new class of salicylic acid derivatives for inhibiting YopH of Yersinia pestis. Bioorganic & Medicinal Chemistry. 22: 6781-8
Sharma N, Everingham S, Zeng LF, et al. (2014) Oncogenic KIT-induced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice. Oncotarget. 5: 6130-41
Zeng LF, Zhang RY, Yu ZH, et al. (2014) Therapeutic potential of targeting the oncogenic SHP2 phosphatase. Journal of Medicinal Chemistry. 57: 6594-609
Chen X, Wang H, Liao HJ, et al. (2014) Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. The Journal of Clinical Investigation. 124: 3295-310
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