Zhong-Yin Zhang
Affiliations: | Biochemistry and Molecular Biology | Indiana University, Bloomington, Bloomington, IN, United States |
Area:
Biochemistry, Analytical Chemistry, Molecular BiologyGoogle:
"Zhong-Yin Zhang"Children
Sign in to add trainee| Jinpeng Sun | grad student | 2001-2006 | (Neurotree) |
| Chad D. Walls | grad student | 2012 | Indiana University |
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Gebregiworgis T, Kano Y, St-Germain J, et al. (2021) The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors. Nature Communications. 12: 6274 |
| Krabill AD, Zhang ZY. (2021) Functional interrogation and therapeutic targeting of protein tyrosine phosphatases. Biochemical Society Transactions. 49: 1723-1734 |
| Xu YF, Chen X, Yang Z, et al. (2021) PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates. Embo Reports. e52141 |
| Chen H, Libring S, Ruddraraju KV, et al. (2020) SHP2 is a multifunctional therapeutic target in drug resistant metastatic breast cancer. Oncogene |
| Zhu G, Xie J, Kong W, et al. (2020) Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation. Cell |
| Li Q, Bai Y, Lyle LT, et al. (2020) Mechanism of PRL2 phosphatase-mediated PTEN degradation and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America |
| Ruddraraju KV, Aggarwal D, Niu C, et al. (2020) Highly Potent and Selective N-aryl Oxamic Acid Based Inhibitors for Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (mPTPB). Journal of Medicinal Chemistry |
| Zhang RY, Yu ZH, Chen L, et al. (2020) Mechanistic insights explain the transforming potential of the T507K substitution in the protein tyrosine phosphatase SHP2. The Journal of Biological Chemistry |
| Li Y, Gardner JJ, Fortney KR, et al. (2019) First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors. Bioorganic & Medicinal Chemistry Letters |
| Kano Y, Gebregiworgis T, Marshall CB, et al. (2019) Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation. Nature Communications. 10: 224 |