Zhong-Yin Zhang

Affiliations: 
Biochemistry and Molecular Biology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Biochemistry, Analytical Chemistry, Molecular Biology
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"Zhong-Yin Zhang"
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Publications

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He R, Yu ZH, Zhang RY, et al. (2015) Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. Acs Medicinal Chemistry Letters. 6: 782-6
He Y, Guo X, Yu ZH, et al. (2015) A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorganic & Medicinal Chemistry. 23: 2798-809
Dodd GT, Decherf S, Loh K, et al. (2015) Leptin and insulin act on POMC neurons to promote the browning of white fat. Cell. 160: 88-104
Paudyal MP, Wu L, Zhang ZY, et al. (2014) A new class of salicylic acid derivatives for inhibiting YopH of Yersinia pestis. Bioorganic & Medicinal Chemistry. 22: 6781-8
Sharma N, Everingham S, Zeng LF, et al. (2014) Oncogenic KIT-induced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice. Oncotarget. 5: 6130-41
Zeng LF, Zhang RY, Yu ZH, et al. (2014) Therapeutic potential of targeting the oncogenic SHP2 phosphatase. Journal of Medicinal Chemistry. 57: 6594-609
Chen X, Wang H, Liao HJ, et al. (2014) Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling. The Journal of Clinical Investigation. 124: 3295-310
Yu ZH, Zhang RY, Walls CD, et al. (2014) Molecular basis of gain-of-function LEOPARD syndrome-associated SHP2 mutations. Biochemistry. 53: 4136-51
Kobayashi M, Bai Y, Dong Y, et al. (2014) PRL2/PTP4A2 phosphatase is important for hematopoietic stem cell self-renewal. Stem Cells (Dayton, Ohio). 32: 1956-67
Liao J, Wu CX, Burlak C, et al. (2014) Parkinson disease-associated mutation R1441H in LRRK2 prolongs the "active state" of its GTPase domain. Proceedings of the National Academy of Sciences of the United States of America. 111: 4055-60
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