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Sheila S. David

Affiliations: 
Biochemistry and Molecular Biology University of California, Davis, Davis, CA 
Area:
Biochemistry, Molecular Biology, Cell Biology, Oncology
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"Sheila David"
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Parents

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Children

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Aurea M. Chu grad student 2011 UC Davis
Lisa M. Engstrom grad student 2011 UC Davis
Megan K. Brinkmeyer grad student 2012 UC Davis
Paige L. McKibbin grad student 2012 UC Davis
Alan G. Raetz grad student 2013 UC Davis

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Publications

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Conlon SG, Khuu C, Trasviña-Arenas CH, et al. (2024) Cellular Repair of Synthetic Analogs of Oxidative DNA Damage Reveals a Key Structure-Activity Relationship of the Cancer-Associated MUTYH DNA Repair Glycosylase. Acs Central Science. 10: 291-301
Eckenroth BE, Bumgarner JD, Matsumoto-Elliott O, et al. (2023) Structural and biochemical insights into NEIL2's preference for abasic sites. Nucleic Acids Research
Demir M, Russelburg LP, Lin WJ, et al. (2023) Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism. Nucleic Acids Research
Lotsof ER, Krajewski AE, Anderson-Steele B, et al. (2022) NEIL1 Recoding due to RNA Editing Impacts Lesion-Specific Recognition and Excision. Journal of the American Chemical Society. 144: 14578-14589
Trasviña-Arenas CH, Demir M, Lin WJ, et al. (2021) Structure, function and evolution of the Helix-hairpin-Helix DNA glycosylase superfamily: Piecing together the evolutionary puzzle of DNA base damage repair mechanisms. Dna Repair. 108: 103231
Jang S, Schaich MA, Khuu C, et al. (2021) Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover. Nucleic Acids Research
Pidugu LS, Bright H, Lin WJ, et al. (2021) Structural Insights into the Mechanism of Base Excision by MBD4. Journal of Molecular Biology. 167097
Yeo J, Lotsof ER, Anderson-Steele BM, et al. (2021) RNA Editing of the Human DNA Glycosylase NEIL1 Alters Its Removal of 5-Hydroxyuracil Lesions in DNA. Biochemistry
Majumdar C, McKibbin PL, Krajewski AE, et al. (2020) Unique Hydrogen Bonding of Adenine with the Oxidatively Damaged Base 8-Oxoguanine Enables Specific Recognition and Repair by DNA Glycosylase MutY. Journal of the American Chemical Society
Zhu RY, Majumdar C, Khuu C, et al. (2020) Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity. Acs Central Science. 6: 1735-1742
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