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Alan P. Fields

Affiliations: 
Biochemistry and Molecular Biology College of Medicine - Mayo Clinic 
Area:
Oncology, Molecular Biology, Biochemistry
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"Alan Fields"
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Amanda M. Butler grad student 2014 College of Medicine - Mayo Clinic

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Jayaraman S, Wu X, Kalari KR, et al. (2023) Endoxifen downregulates AKT phosphorylation through protein kinase C beta 1 inhibition in ERα+ breast cancer. Npj Breast Cancer. 9: 101
Inman KS, Liu Y, Scotti Buzhardt ML, et al. (2022) Regulates Autophagy and Pancreatic Tumorigenesis in Mice. Cancers. 14
Kenchappa RS, Liu Y, Argenziano MG, et al. (2021) Protein kinase C and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities. Cell Reports. 37: 110054
Cook DR, Kang M, Martin TD, et al. (2021) Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth. Cancer Research
Limzerwala JF, Jeganathan KB, Kloeber JA, et al. (2020) FoxM1 insufficiency hyperactivates Ect2-RhoA-mDia1 signaling to drive cancer. Nature Cancer. 1: 1010-1024
Liu Y, Justilien V, Fields AP, et al. (2020) Recurrent copy number gains drive PKCι expression and PKCι-dependent oncogenic signaling in human cancers. Advances in Biological Regulation. 78: 100754
Justilien V, Lewis KC, Meneses KM, et al. (2020) Protein kinase Cι promotes UBF1-ECT2 binding on ribosomal DNA to drive rRNA synthesis and transformed growth of non-small cell lung cancer cells. The Journal of Biological Chemistry
Liu Y, Yin N, Wang X, et al. (2020) Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma. Cell Reports. 30: 771-782.e6
Yin N, Liu Y, Khoor A, et al. (2019) Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma. Cancer Cell. 36: 692-693
Yin N, Liu Y, Murray NR, et al. (2019) Oncogenic protein kinase Cι signaling mechanisms in lung cancer: Implications for improved therapeutic strategies. Advances in Biological Regulation. 100656
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