Crystal S. Conn, Ph.D.
Affiliations: | 2013 | Molecular Biology and Genetics | Cornell University, Ithaca, NY, United States |
Area:
Molecular Biology, BiochemistryGoogle:
"Crystal Conn"Parents
Sign in to add mentor| Shu-Bing Qian | grad student | 2013 | Cornell | |
| (Elucidating the regulatory mechanisms of the mammalian target of rapamycin complex 1 (mTORC1) in protein homeostasis.) | ||||
| Davide Ruggero | post-doc | 2013-2019 | UCSF School of Medicine | |
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Publications
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| Lines CL, McGrath MJ, Dorwart T, et al. (2023) The integrated stress response in cancer progression: a force for plasticity and resistance. Frontiers in Oncology. 13: 1206561 |
| Chiu H, Buono R, Jackson LV, et al. (2021) Reduced eIF4E function impairs B-cell leukemia without altering normal B-lymphocyte function. Iscience. 24: 102748 |
| Conn CS, Yang H, Tom HJ, et al. (2021) The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity. Nature Metabolism. 3: 244-257 |
| Tameire F, Verginadis II, Leli NM, et al. (2019) Author Correction: ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nature Cell Biology |
| Tameire F, Verginadis II, Leli NM, et al. (2019) ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nature Cell Biology. 21: 889-899 |
| Wei J, Kishton RJ, Angel M, et al. (2019) Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance. Molecular Cell |
| Nguyen HG, Conn CS, Kye Y, et al. (2018) Development of a stress response therapy targeting aggressive prostate cancer. Science Translational Medicine. 10 |
| Gwinn DM, Lee AG, Briones-Martin-Del-Campo M, et al. (2018) Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase. Cancer Cell. 33: 91-107.e6 |
| Conn CS, Nguyen HG, Kye Y, et al. (2017) Abstract A25: Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development Cancer Research. 77 |
| Truillet C, Cunningham JT, Parker MF, et al. (2016) Non-invasive measurement of mTORC1 signaling with 89Zr-transferrin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |