Tobi L. Limke, Ph.D.

2001 Michigan State University, East Lansing, MI 
Toxicology, Cell Biology
"Tobi Limke"


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William D. Atchison grad student 2001 Michigan State
 (Relationship between methylmercury-induced disruption of intracellular calcium and neuronal death.)
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Limke TL, Atchison WD. (2009) Application of single-cell microfluorimetry to neurotoxicology assays. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit 12.15
Brazel CY, Limke TL, Osborne JK, et al. (2005) Sox2 expression defines a heterogeneous population of neurosphere-forming cells in the adult murine brain. Aging Cell. 4: 197-207
Mi R, Luo Y, Cai J, et al. (2005) Immortalized neural stem cells differ from nonimmortalized cortical neurospheres and cerebellar granule cell progenitors. Experimental Neurology. 194: 301-19
Limke TL, Heidemann SR, Atchison WD. (2004) Disruption of intraneuronal divalent cation regulation by methylmercury: are specific targets involved in altered neuronal development and cytotoxicity in methylmercury poisoning? Neurotoxicology. 25: 741-60
Limke TL, Bearss JJ, Atchison WD. (2004) Acute exposure to methylmercury causes Ca2+ dysregulation and neuronal death in rat cerebellar granule cells through an M3 muscarinic receptor-linked pathway. Toxicological Sciences : An Official Journal of the Society of Toxicology. 80: 60-8
Limke TL, Rao MS. (2003) Neural stem cell therapy in the aging brain: pitfalls and possibilities. Journal of Hematotherapy & Stem Cell Research. 12: 615-23
Limke TL, Cai J, Miura T, et al. (2003) Distinguishing features of progenitor cells in the late embryonic and adult hippocampus. Developmental Neuroscience. 25: 257-72
Cai J, Limke TL, Ginis I, et al. (2003) Identifying and tracking neural stem cells. Blood Cells, Molecules & Diseases. 31: 18-27
Limke TL, Otero-Montañez JK, Atchison WD. (2003) Evidence for interactions between intracellular calcium stores during methylmercury-induced intracellular calcium dysregulation in rat cerebellar granule neurons. The Journal of Pharmacology and Experimental Therapeutics. 304: 949-58
Limke TL, Atchison WD. (2002) Acute exposure to methylmercury opens the mitochondrial permeability transition pore in rat cerebellar granule cells. Toxicology and Applied Pharmacology. 178: 52-61
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