Lauren Drowley, Ph.D.

Affiliations: 
2009 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Cell Biology, Pathology
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"Lauren Drowley"

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Johnny Huard grad student 2009 University of Pittsburgh
 (Cellular cardiomyoplasty based on muscle stem cells: Implications for therapy.)
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Publications

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Schade D, Drowley L, Wang QD, et al. (2022) Phenotypic screen identifies FOXO inhibitor to counteract maturation and promote expansion of human iPS cell-derived cardiomyocytes. Bioorganic & Medicinal Chemistry. 65: 116782
Ding M, Andersson H, Martinsson S, et al. (2020) Aligned nanofiber scaffolds improve functionality of cardiomyocytes differentiated from human induced pluripotent stem cell-derived cardiac progenitor cells. Scientific Reports. 10: 13575
Drowley L, McPheat J, Nordqvist A, et al. (2019) Discovery of Retinoic Acid Receptor Agonists as Proliferators of Cardiac Progenitor Cells Through a Phenotypic Screening Approach. Stem Cells Translational Medicine
Yu JSL, Palano G, Lim C, et al. (2019) CRISPR-KO screen identifies Dmap1 as a regulator of chemically-induced reprogramming and differentiation of cardiac progenitors. Stem Cells (Dayton, Ohio)
Mills RJ, Parker BL, Quaife-Ryan GA, et al. (2019) Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway. Cell Stem Cell
Laengle D, Werner TR, Wesseler F, et al. (2019) Towards second generation cardiomyogenic and anti-cardiofibrotic 1,4-dihydropyridine-class of TGFβ inhibitors. Chemmedchem
Woo LA, Tkachenko S, Ding M, et al. (2018) High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets. Journal of Molecular and Cellular Cardiology
Mills RJ, Titmarsh DM, Koenig X, et al. (2017) Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest. Proceedings of the National Academy of Sciences of the United States of America
Paunovic AI, Drowley L, Nordqvist A, et al. (2017) Phenotypic Screen for Cardiac Regeneration Identifies Molecules with Differential Activity in Human Epicardium-Derived Cells versus Cardiac Fibroblasts. Acs Chemical Biology. 12: 132-141
Bao X, Lian X, Hacker TA, et al. (2016) Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions. Nature Biomedical Engineering. 1
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