Marina Ayrapetov, Ph.D.

Affiliations: 
2006 University of Rhode Island, Providence, RI, United States 
Area:
Biochemistry, Cell Biology, Molecular Biology
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"Marina Ayrapetov"

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Gongqin Sun grad student 2006 University of Rhode Island
 (Structural and functional studies of the Csk and Src family protein tyrosine kinases.)
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Publications

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Chapdelaine AG, Ku GC, Sun G, et al. (2023) The Targeted Degradation of BRAF V600E Reveals the Mechanisms of Resistance to BRAF-Targeted Treatments in Colorectal Cancer Cells. Cancers. 15
Sun G, Ayrapetov MK. (2023) Dissection of the catalytic and regulatory structure-function relationships of Csk protein tyrosine kinase. Frontiers in Cell and Developmental Biology. 11: 1148352
Ku GC, Chapdelaine AG, Ayrapetov MK, et al. (2022) Identification of Lethal Inhibitors and Inhibitor Combinations for Mono-Driver versus Multi-Driver Triple-Negative Breast Cancer Cells. Cancers. 14
Huang C, Zhang Z, Chen L, et al. (2018) Acetylation within the N- and C-terminal domains of Src regulate distinct roles of STAT3-mediated tumorigenesis. Cancer Research
Ahmadibeni Y, Hanley M, White M, et al. (2007) Metal-binding properties of a dicysteine-containing motif in protein tyrosine kinases. Chembiochem : a European Journal of Chemical Biology. 8: 1592-605
Ayrapetov MK, Wang YH, Lin X, et al. (2006) Conformational basis for SH2-Tyr(P)527 binding in Src inactivation. The Journal of Biological Chemistry. 281: 23776-84
Wang YH, Ayrapetov MK, Lin X, et al. (2006) A new strategy to produce active human Src from bacteria for biochemical study of its regulation. Biochemical and Biophysical Research Communications. 346: 606-11
Lee S, Ayrapetov MK, Kemble DJ, et al. (2006) Docking-based substrate recognition by the catalytic domain of a protein tyrosine kinase, C-terminal Src kinase (Csk). The Journal of Biological Chemistry. 281: 8183-9
Lin X, Ayrapetov MK, Sun G. (2005) Characterization of the interactions between the active site of a protein tyrosine kinase and a divalent metal activator. Bmc Biochemistry. 6: 25
Ye G, Ayrapetov M, Nam NH, et al. (2005) Solid-phase binding assays of peptides using EGFP-Src SH2 domain fusion protein and biotinylated Src SH2 domain. Bioorganic & Medicinal Chemistry Letters. 15: 4994-7
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