Alan G. Raetz, Ph.D.
Affiliations: | 2013 | Biochemistry and Molecular Biology | University of California, Davis, Davis, CA |
Area:
Biochemistry, Molecular Biology, Cell Biology, OncologyGoogle:
"Alan Raetz"Parents
Sign in to add mentor| Sheila S. David | grad student | 2013 | UC Davis | |
| (The role of mutyh in oxidative dna damage repair and alkylative dna damage response in mammalian cells.) | ||||
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| Conlon SG, Khuu C, Trasviña-Arenas CH, et al. (2024) Cellular Repair of Synthetic Analogs of Oxidative DNA Damage Reveals a Key Structure-Activity Relationship of the Cancer-Associated MUTYH DNA Repair Glycosylase. Acs Central Science. 10: 291-301 |
| Tsutakawa SE, Sarker AH, Ng C, et al. (2020) Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations. Proceedings of the National Academy of Sciences of the United States of America |
| Raetz AG, Banda DM, Ma X, et al. (2020) The DNA repair enzyme MUTYH potentiates cytotoxicity of the alkylating agent MNNG by interacting with abasic sites. The Journal of Biological Chemistry |
| Raetz AG, David SS. (2019) When you're strange: Unusual features of the MUTYH glycosylase and implications in cancer. Dna Repair. 80: 16-25 |
| Majumdar C, Nuñez NN, Raetz AG, et al. (2018) Cellular Assays for Studying the Fe-S Cluster Containing Base Excision Repair Glycosylase MUTYH and Homologs. Methods in Enzymology. 599: 69-99 |
| Shen Y, McMackin MZ, Shan Y, et al. (2016) Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34. Plos One. 11: e0151026 |
| Engstrom LM, Brinkmeyer MK, Ha Y, et al. (2014) A zinc linchpin motif in the MUTYH glycosylase interdomain connector is required for efficient repair of DNA damage. Journal of the American Chemical Society. 136: 7829-32 |
| Raetz AG, Xie Y, Kundu S, et al. (2012) Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells. Carcinogenesis. 33: 2301-9 |