Adam R. Hersperger, Ph.D.

2010 University of Pennsylvania, Philadelphia, PA, United States 
Microbiology Biology, Immunology
"Adam Hersperger"


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Michael R. Betts grad student 2010 Penn
 (Insights into the cytotoxic potential of human CD8+ T cells: Implications for virologic control of HIV.)
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Hand ES, Haller SL, Peng C, et al. (2015) Ectopic expression of vaccinia virus E3 and K3 cannot rescue ectromelia virus replication in rabbit RK13 cells. Plos One. 10: e0119189
Siciliano NA, Hersperger AR, Lacuanan AM, et al. (2014) Impact of distinct poxvirus infections on the specificities and functionalities of CD4+ T cell responses. Journal of Virology. 88: 10078-91
Hersperger AR, Siciliano NA, DeHaven BC, et al. (2014) Epithelial immunization induces polyfunctional CD8+ T cells and optimal mousepox protection. Journal of Virology. 88: 9472-5
Fang M, Siciliano NA, Hersperger AR, et al. (2012) Perforin-dependent CD4+ T-cell cytotoxicity contributes to control a murine poxvirus infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 9983-8
Hersperger AR, Siciliano NA, Eisenlohr LC. (2012) Comparable polyfunctionality of ectromelia virus- and vaccinia virus-specific murine T cells despite markedly different in vivo replication and pathogenicity. Journal of Virology. 86: 7298-309
Hersperger AR, Migueles SA, Betts MR, et al. (2011) Qualitative features of the HIV-specific CD8+ T-cell response associated with immunologic control. Current Opinion in Hiv and Aids. 6: 169-73
Hersperger AR, Martin JN, Shin LY, et al. (2011) Increased HIV-specific CD8+ T-cell cytotoxic potential in HIV elite controllers is associated with T-bet expression. Blood. 117: 3799-808
Hersperger AR, Pereyra F, Nason M, et al. (2010) Perforin expression directly ex vivo by HIV-specific CD8 T-cells is a correlate of HIV elite control. Plos Pathogens. 6: e1000917
Makedonas G, Hutnick N, Haney D, et al. (2010) Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells. Plos Pathogens. 6: e1000798
Makedonas G, Banerjee PP, Pandey R, et al. (2009) Rapid up-regulation and granule-independent transport of perforin to the immunological synapse define a novel mechanism of antigen-specific CD8+ T cell cytotoxic activity. Journal of Immunology (Baltimore, Md. : 1950). 182: 5560-9
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