Jose L. Morales, Ph.D.

2008 Pennsylvania State University, State College, PA, United States 
Molecular Biology, Biochemistry, Cell Biology
"Jose Morales"


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Gary H. Perdew grad student 2008 Penn State
 (Regulation of the aryl hydrocarbon receptor protein levels and signal transduction pathways.)
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Huang W, Morales JL, Gazivoda VP, et al. (2015) Nonreceptor tyrosine kinases ITK and BTK negatively regulate mast cell proinflammatory responses to lipopolysaccharide. The Journal of Allergy and Clinical Immunology
Yao PL, Morales JL, Zhu B, et al. (2014) Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity. Molecular Cancer Therapeutics. 13: 1008-17
Huang W, Morales JL, Gazivoda VP, et al. (2013) The zinc-binding region of IL-2 inducible T cell kinase (Itk) is required for interaction with Gα13 and activation of serum response factor. The International Journal of Biochemistry & Cell Biology. 45: 1074-82
Peters JM, Morales JL, Gonzalez FJ. (2011) Modulation of gastrointestinal inflammation and colorectal tumorigenesis by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ). Drug Discovery Today. Disease Mechanisms. 8: e85-e93
Law M, Morales JL, Mottram LF, et al. (2011) Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2. The International Journal of Biochemistry & Cell Biology. 43: 1228-39
Iyer AS, Morales JL, Huang W, et al. (2011) Absence of Tec family kinases interleukin-2 inducible T cell kinase (Itk) and Bruton's tyrosine kinase (Btk) severely impairs Fc epsilonRI-dependent mast cell responses. The Journal of Biological Chemistry. 286: 9503-13
Perdew GH, Hollingshead BD, Dinatale BC, et al. (2010) Estrogen receptor expression is required for low-dose resveratrol-mediated repression of aryl hydrocarbon receptor activity. The Journal of Pharmacology and Experimental Therapeutics. 335: 273-83
Sahu N, Morales JL, Fowell D, et al. (2010) Modeling susceptibility versus resistance in allergic airway disease reveals regulation by Tec kinase Itk. Plos One. 5: e11348
Mercer JC, Qi Q, Mottram LF, et al. (2010) Chemico-genetic identification of drebrin as a regulator of calcium responses. The International Journal of Biochemistry & Cell Biology. 42: 337-45
Murray IA, Morales JL, Flaveny CA, et al. (2010) Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity. Molecular Pharmacology. 77: 247-54
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