Jose L. Morales, Ph.D.
Affiliations: | 2008 | Pennsylvania State University, State College, PA, United States |
Area:
Molecular Biology, Biochemistry, Cell BiologyGoogle:
"Jose Morales"Parents
Sign in to add mentor| Gary H. Perdew | grad student | 2008 | Penn State | |
| (Regulation of the aryl hydrocarbon receptor protein levels and signal transduction pathways.) | ||||
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Publications
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| Yao PL, Morales JL, Gonzalez FJ, et al. (2016) Peroxisome proliferator-activated receptor-β/δ modulates mast cell phenotype. Immunology |
| Yao PL, Morales JL, Zhu B, et al. (2014) Activation of peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) inhibits human breast cancer cell line tumorigenicity. Molecular Cancer Therapeutics. 13: 1008-17 |
| Peters JM, Morales JL, Gonzalez FJ. (2011) Modulation of gastrointestinal inflammation and colorectal tumorigenesis by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ). Drug Discovery Today. Disease Mechanisms. 8: e85-e93 |
| Perdew GH, Hollingshead BD, Dinatale BC, et al. (2010) Estrogen receptor expression is required for low-dose resveratrol-mediated repression of aryl hydrocarbon receptor activity. The Journal of Pharmacology and Experimental Therapeutics. 335: 273-83 |
| Murray IA, Morales JL, Flaveny CA, et al. (2010) Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity. Molecular Pharmacology. 77: 247-54 |
| Chiaro CR, Morales JL, Prabhu KS, et al. (2008) Leukotriene A4 metabolites are endogenous ligands for the Ah receptor. Biochemistry. 47: 8445-55 |
| Morales JL, Krzeminski J, Amin S, et al. (2008) Characterization of the antiallergic drugs 3-[2-(2-phenylethyl) benzoimidazole-4-yl]-3-hydroxypropanoic acid and ethyl 3-hydroxy-3-[2-(2-phenylethyl)benzoimidazol-4-yl]propanoate as full aryl hydrocarbon receptor agonists. Chemical Research in Toxicology. 21: 472-82 |
| Morales JL, Perdew GH. (2007) Carboxyl terminus of hsc70-interacting protein (CHIP) can remodel mature aryl hydrocarbon receptor (AhR) complexes and mediate ubiquitination of both the AhR and the 90 kDa heat-shock protein (hsp90) in vitro. Biochemistry. 46: 610-21 |