Julie Lessard, Ph.D.

2003 Université de Montréal, Montréal, Canada 
Molecular Biology
"Julie Lessard"


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Guy Sauvageau grad student 2003 Université de Montréal
 (Expression et fonction des genes du groupe Polycomb (PcG) dans l'hematopoiese normale et leucemique.)
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Priam P, Krasteva V, Rousseau P, et al. (2017) SMARCD2 subunit of SWI/SNF chromatin-remodeling complexes mediates granulopoiesis through a CEBPɛ dependent mechanism. Nature Genetics
Buscarlet M, Krasteva V, Ho L, et al. (2014) Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance. Blood. 123: 1720-8
Trompouki E, King KY, Will B, et al. (2014) Bloody signals: From birth to disease and death Experimental Hematology. 42: 989-994
Lessard J, Charest A. (2013) EGFR and tumor suppressor function in brain cancer development Neuromethods. 77: 217-225
Krasteva V, Buscarlet M, Diaz-Tellez A, et al. (2012) The BAF53a subunit of SWI/SNF-like BAF complexes is essential for hemopoietic stem cell function. Blood. 120: 4720-32
Jun HJ, Acquaviva J, Chi D, et al. (2012) Acquired MET expression confers resistance to EGFR inhibition in a mouse model of glioblastoma multiforme. Oncogene. 31: 3039-50
Acquaviva J, Jun HJ, Lessard J, et al. (2011) Chronic activation of wild-type epidermal growth factor receptor and loss of Cdkn2a cause mouse glioblastoma formation. Cancer Research. 71: 7198-206
Lessard JA, Crabtree GR. (2010) Chromatin regulatory mechanisms in pluripotency. Annual Review of Cell and Developmental Biology. 26: 503-32
Krosl J, Mamo A, Chagraoui J, et al. (2010) A mutant allele of the Swi/Snf member BAF250a determines the pool size of fetal liver hemopoietic stem cell populations. Blood. 116: 1678-84
Ho L, Ronan JL, Wu J, et al. (2009) An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proceedings of the National Academy of Sciences of the United States of America. 106: 5181-6
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