Lawrence L. LeClaire, Ph.D.

Affiliations: 
2002 Florida State University, Tallahassee, FL, United States 
Area:
Cell Biology
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"Lawrence LeClaire"

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Thomas M. Roberts grad student 2002 Florida State
 (Isolation of the integral membrane phosphoprotein required for polymerization of major sperm protein from Ascaris suum.)
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Publications

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Michard C, LeClaire LL, Doublet P. (2017) ARP2/3 Phosphorylation Assay in the Presence of Recombinant Bacterial Effectors. Bio-Protocol. 7: e2208
LeClaire LL, Fortwendel JR. (2015) Differential Support of Aspergillus fumigatus Morphogenesis by Yeast and Human Actins. Plos One. 10: e0142535
Michard C, Sperandio D, Baïlo N, et al. (2015) The Legionella Kinase LegK2 Targets the ARP2/3 Complex To Inhibit Actin Nucleation on Phagosomes and Allow Bacterial Evasion of the Late Endocytic Pathway. Mbio. 6: e00354-15
LeClaire LL, Rana M, Baumgartner M, et al. (2015) The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit. The Journal of Cell Biology. 208: 161-70
Narayanan A, LeClaire LL, Barber DL, et al. (2011) Phosphorylation of the Arp2 subunit relieves auto-inhibitory interactions for Arp2/3 complex activation. Plos Computational Biology. 7: e1002226
LeClaire LL, Baumgartner M, Iwasa JH, et al. (2008) Phosphorylation of the Arp2/3 complex is necessary to nucleate actin filaments. The Journal of Cell Biology. 182: 647-54
Rodriguez MA, LeClaire LL, Roberts TM. (2005) Preparing to move: assembly of the MSP amoeboid motility apparatus during spermiogenesis in Ascaris. Cell Motility and the Cytoskeleton. 60: 191-9
LeClaire LL, Stewart M, Roberts TM. (2003) A 48 kDa integral membrane phosphoprotein orchestrates the cytoskeletal dynamics that generate amoeboid cell motility in Ascaris sperm. Journal of Cell Science. 116: 2655-63
Haaf A, LeClaire L, Roberts G, et al. (1998) Solution structure of the motile major sperm protein (MSP) of Ascaris suum - evidence for two manganese binding sites and the possible role of divalent cations in filament formation. Journal of Molecular Biology. 284: 1611-24
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