Eric S. Witze, Ph.D.
Affiliations: | 2003 | University of California, Santa Barbara, Santa Barbara, CA, United States |
Area:
Cell Biology, Molecular BiologyGoogle:
"Eric Witze"Parents
Sign in to add mentor| Joel H. Rothman | grad student | 2003 | UC Santa Barbara | |
| (Identification and characterization of PLP-1, an asymmetrically distributed protein that synergizes with the Wnt pathway to specify endoderm in Caenorhabditis elegans.) | ||||
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Publications
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| Kadry YA, Lee JY, Witze ES. (2021) Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis. Open Biology. 11: 210033 |
| Kharbanda A, Walter DM, Gudiel AA, et al. (2020) Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis. Science Signaling. 13 |
| Sadeghi RS, Kulej K, Kathayat RS, et al. (2018) Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior. Elife. 7 |
| Stypulkowski E, Asangani IA, Witze ES. (2018) The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division. Science Signaling. 11 |
| Sadeghi RS, Kulej K, Kathayat RS, et al. (2018) Author response: Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior Elife |
| Rebecca VW, Nicastri MC, McLaughlin N, et al. (2017) A unified approach to targeting the lysosome's degradative and growth signaling roles. Cancer Discovery |
| Kharbanda A, Runkle K, Wang W, et al. (2017) Induced sensitivity to EGFR inhibitors is mediated by palmitoylated cysteine 1025 of EGFR and requires oncogenic Kras. Biochemical and Biophysical Research Communications |
| Runkle KB, Witze ES. (2016) Wnt-Dependent Control of Cell Polarity in Cultured Cells. Methods in Molecular Biology (Clifton, N.J.). 1481: 61-8 |
| Runkle KB, Kharbanda A, Stypulkowski E, et al. (2016) Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling. Molecular Cell. 62: 385-396 |
| He X, Wang L, Yan J, et al. (2015) Menin Localization In Cell Membrane Compartment. Cancer Biology & Therapy. 0 |