William E. Dowdle, Ph.D.

Affiliations: 
2012 Developmental Biology University of California, San Francisco, San Francisco, CA 
Area:
Biochemistry, Genetics, Human Development
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"William Dowdle"

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Jeremy F. Reiter grad student 2012 UCSF
 (Primary cilia as signaling organelles in development and disease.)
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Publications

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Roberson EC, Dowdle WE, Ozanturk A, et al. (2015) TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone. The Journal of Cell Biology. 209: 129-42
Saqui-Salces M, Dowdle WE, Reiter JF, et al. (2012) A high-fat diet regulates gastrin and acid secretion through primary cilia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3127-39
Reiter J, Garcia-Gonzalo F, Corbit K, et al. (2012) A transition zone complex of ciliopathy proteins regulates ciliary composition Cilia. 1: 1-1
Saqui-Salces M, Dowdle WE, Reiter JF, et al. (2012) 201 Food Intake Stimulates Gastrin and Acid Secretion Through Primary Cilia Gastroenterology. 142: S-49-S-50
Dowdle WE, Robinson JF, Kneist A, et al. (2011) Disruption of a ciliary B9 protein complex causes Meckel syndrome. American Journal of Human Genetics. 89: 94-110
Croyle MJ, Lehman JM, O'Connor AK, et al. (2011) Role of epidermal primary cilia in the homeostasis of skin and hair follicles. Development (Cambridge, England). 138: 1675-85
Saqui-Salces M, Dowdle WE, Reiter JF, et al. (2011) Mice With Gastric Hyperplasia Develop Obesity, Fatty Liver and Large Pancreatic Islets Gastroenterology. 140: S-332
Saqui-Salces M, Dowdle WE, Reiter JF, et al. (2011) Disruption of Primary Cilia Induces Gastric Mucosal Hyperplasia Gastroenterology. 140: S-93
Shin S, Dimitri CA, Yoon SO, et al. (2010) ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling events. Molecular Cell. 38: 114-27
Corbit KC, Shyer AE, Dowdle WE, et al. (2008) Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nature Cell Biology. 10: 70-6
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