Yvette Y. Yien, Ph.D.

Affiliations: 
2011 Developmental and Stem Cell Biology (DSCB) Mount Sinai School of Medicine, New York, NY 
Area:
Biochemistry
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"Yvette Yien"

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James J. Bieker grad student 2011 Mount Sinai
 (Regulation of the Erythroid Kruppel-Like Factor (EKLF): Beyond the basal transcription machinery.)
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Publications

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Yien YY, Paw BH. (2016) A role for iron deficiency in dopaminergic neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 113: 3417-8
Yien YY, Ringel AR, Paw BH. (2015) Mitochondrial transport of protoporphyrinogen IX in erythroid cells. Oncotarget. 6: 20742-3
Kardon JR, Yien YY, Huston NC, et al. (2015) Mitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis. Cell. 161: 858-67
Chung J, Bauer DE, Ghamari A, et al. (2015) The mTORC1/4E-BP pathway coordinates hemoglobin production with L-leucine availability. Science Signaling. 8: ra34
Yien YY, Gnanapragasam MN, Gupta R, et al. (2015) Alternative splicing of EKLF/KLF1 in murine primary erythroid tissues. Experimental Hematology. 43: 65-70
Yien YY, Robledo RF, Schultz IJ, et al. (2014) TMEM14C is required for erythroid mitochondrial heme metabolism. The Journal of Clinical Investigation. 124: 4294-304
Canver MC, Bauer DE, Dass A, et al. (2014) Characterization of genomic deletion efficiency mediated by clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 nuclease system in mammalian cells. The Journal of Biological Chemistry. 289: 21312-24
Hildick-Smith GJ, Cooney JD, Garone C, et al. (2013) Macrocytic anemia and mitochondriopathy resulting from a defect in sideroflexin 4. American Journal of Human Genetics. 93: 906-14
Chen C, Garcia-Santos D, Ishikawa Y, et al. (2013) Snx3 regulates recycling of the transferrin receptor and iron assimilation. Cell Metabolism. 17: 343-52
Yien YY, Bieker JJ. (2013) EKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination. Molecular and Cellular Biology. 33: 4-13
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