Kari M. Morrissey, Ph.D.

Affiliations: 
2013 Pharmaceutical Sciences and Pharmacogenomics University of California, San Francisco, San Francisco, CA 
Area:
Pharmacy
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"Kari Morrissey"

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Kathleen M. Giacomini grad student 2013 UCSF
 (Organic Cation Transporters in Drug Disposition and Response.)
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Publications

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Morrissey KM, Stocker SL, Chen EC, et al. (2015) The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers. Clinical Pharmacokinetics
Smith RP, Eckalbar WL, Morrissey KM, et al. (2014) Genome-wide discovery of drug-dependent human liver regulatory elements. Plos Genetics. 10: e1004648
Chen L, Shu Y, Liang X, et al. (2014) OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proceedings of the National Academy of Sciences of the United States of America. 111: 9983-8
Stocker SL, Morrissey KM, Yee SW, et al. (2013) The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin. Clinical Pharmacology and Therapeutics. 93: 186-94
Wittwer MB, Zur AA, Khuri N, et al. (2013) Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. Journal of Medicinal Chemistry. 56: 781-95
Morrissey KM, Stocker SL, Wittwer MB, et al. (2013) Renal transporters in drug development. Annual Review of Pharmacology and Toxicology. 53: 503-29
Morrissey KM, Wen CC, Johns SJ, et al. (2012) The UCSF-FDA TransPortal: a public drug transporter database. Clinical Pharmacology and Therapeutics. 92: 545-6
Matsson P, Yee SW, Markova S, et al. (2012) Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping. The Pharmacogenomics Journal. 12: 214-26
Choi JH, Yee SW, Ramirez AH, et al. (2011) A common 5'-UTR variant in MATE2-K is associated with poor response to metformin. Clinical Pharmacology and Therapeutics. 90: 674-84
Miller WL, Agrawal V, Sandee D, et al. (2011) Consequences of POR mutations and polymorphisms. Molecular and Cellular Endocrinology. 336: 174-9
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