Danielle R. Cook, Ph.D.

Affiliations: 
2013 Pharmaceutical Sciences University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
General Biology, Cell Biology, Oncology
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"Danielle Cook"

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Channing J. Der grad student 2013 UNC Chapel Hill
 (Mechanisms of Ect2 Regulation in Cytokinesis and Oncogenesis.)
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Publications

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Cook DR, Kang M, Martin TD, et al. (2021) Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth. Cancer Research
Yin Y, Boesteanu AC, Binder ZA, et al. (2018) Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas. Molecular Therapy Oncolytics. 11: 20-38
Martin TD, Cook DR, Choi MY, et al. (2017) A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells. Cell Reports. 20: 427-438
Yin Y, Boesteanu A, Xu C, et al. (2017) Combinatorial IL13Rα2 chimeric antigen receptor-T cells plus checkpoint blockade to treat solid tumors in murine and canine models. Journal of Clinical Oncology. 35: 152-152
Fraietta JA, Beckwith KA, Patel PR, et al. (2016) Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia. Blood
Cook DR, Rossman KL, Der CJ. (2014) Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease. Oncogene. 33: 4021-35
Huff LP, Decristo MJ, Trembath D, et al. (2013) The Role of Ect2 Nuclear RhoGEF Activity in Ovarian Cancer Cell Transformation. Genes & Cancer. 4: 460-75
Cook DR, Solski PA, Bultman SJ, et al. (2011) The ect2 rho Guanine nucleotide exchange factor is essential for early mouse development and normal cell cytokinesis and migration. Genes & Cancer. 2: 932-42
Anderson LD, Cook DR, Yamamoto TN, et al. (2011) Identification of MAGE-C1 (CT-7) epitopes for T-cell therapy of multiple myeloma. Cancer Immunology, Immunotherapy : Cii. 60: 985-97
Anderson LD, Cook DR, Berger C, et al. (2007) Use of Gene-Modified T-Cells as Antigen Presenting Cells (T-APC) for Vaccination Against Myeloma Antigens. Blood. 110: 2758-2758
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