William C. Comb, Ph.D.

Affiliations: 
2011 Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Genetics, Molecular Biology, Biochemistry, Cell Biology
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"William Comb"

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Albert S. Baldwin grad student 2011 UNC Chapel Hill
 (Examining novel roles for the IkappaB kinase in coordinating the cellular response to metabolic stress.)
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Publications

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Schweitzer LD, Comb WC, Bar-Peled L, et al. (2015) Disruption of the Rag-Ragulator Complex by c17orf59 Inhibits mTORC1. Cell Reports. 12: 1445-55
Comb WC, Hutti JE, Cogswell P, et al. (2012) p85α SH2 domain phosphorylation by IKK promotes feedback inhibition of PI3K and Akt in response to cellular starvation. Molecular Cell. 45: 719-30
Comb WC, Cogswell P, Sitcheran R, et al. (2011) IKK-dependent, NF-κB-independent control of autophagic gene expression. Oncogene. 30: 1727-32
Sitcheran R, Comb WC, Cogswell PC, et al. (2008) Essential role for epidermal growth factor receptor in glutamate receptor signaling to NF-kappaB. Molecular and Cellular Biology. 28: 5061-70
Herscovitch M, Comb W, Ennis T, et al. (2008) Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347. Biochemical and Biophysical Research Communications. 367: 103-8
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