Jennifer S. Tront, Ph.D.

2007 Temple University, Philadelphia, PA, United States 
Molecular Biology
"Jennifer Tront"


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Dan A. Liebermann grad student 2007 Temple University
 (The role of the Gadd45 family of genes in modulating tumor development.)
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Tront JS, Willis A, Huang Y, et al. (2013) Gadd45a levels in human breast cancer are hormone receptor dependent. Journal of Translational Medicine. 11: 131
Sultan FA, Wang J, Tront J, et al. (2012) Genetic deletion of Gadd45b, a regulator of active DNA demethylation, enhances long-term memory and synaptic plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17059-66
Salerno DM, Tront JS, Hoffman B, et al. (2012) Gadd45a and Gadd45b modulate innate immune functions of granulocytes and macrophages by differential regulation of p38 and JNK signaling. Journal of Cellular Physiology. 227: 3613-20
Liebermann DA, Tront JS, Sha X, et al. (2011) Gadd45 stress sensors in malignancy and leukemia. Critical Reviews in Oncogenesis. 16: 129-40
Tront JS, Huang Y, Fornace AJ, et al. (2010) Gadd45a functions as a promoter or suppressor of breast cancer dependent on the oncogenic stress. Cancer Research. 70: 9671-81
Cretu A, Sha X, Tront J, et al. (2009) Stress sensor Gadd45 genes as therapeutic targets in cancer. Cancer Therapy. 7: 268-276
Xiong Y, Liebermann DA, Tront JS, et al. (2009) Gadd45a stress signaling regulates sFlt-1 expression in preeclampsia. Journal of Cellular Physiology. 220: 632-9
Engel N, Tront JS, Erinle T, et al. (2009) Conserved DNA methylation in Gadd45a(-/-) mice. Epigenetics. 4: 98-9
Tront JS, Hoffman B, Liebermann DA. (2006) Gadd45a suppresses Ras-driven mammary tumorigenesis by activation of c-Jun NH2-terminal kinase and p38 stress signaling resulting in apoptosis and senescence. Cancer Research. 66: 8448-54
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