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Randall W. King

Affiliations: 
Cell Biology Harvard Medical School, Boston, MA, United States 
Area:
Mitosis, cell cycle
Website:
http://king.med.harvard.edu/
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"Randall King"

Parents

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Marc W. Kirschner grad student 1988-1995 UCSF

Children

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Nathaniel A. Hathaway grad student 2007 Harvard
Xing Zeng grad student 2011 Harvard
Nevena Dimova grad student 2012 Harvard
Gregory P. Tochtrop post-doc 2002-2006 Harvard (Chemistry Tree)
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Publications

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Manohar S, Yu Q, Gygi SP, et al. (2020) The insulin receptor adaptor IRS2 is an APC/C substrate that promotes cell cycle protein expression and a robust spindle assembly checkpoint. Molecular & Cellular Proteomics : McP
Richeson KV, Bodrug T, Sackton KL, et al. (2020) Paradoxical mitotic exit induced by a small molecule inhibitor of APC/C. Nature Chemical Biology
Dukovski D, Villella A, Bastos C, et al. (2020) Amplifiers co-translationally enhance CFTR biosynthesis via PCBP1-mediated regulation of CFTR mRNA. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society
Boselli M, Lee BH, Robert J, et al. (2017) An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. The Journal of Biological Chemistry
Lee BH, Lu Y, Prado MA, et al. (2016) USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites. Nature
Lub S, Maes A, Maes K, et al. (2015) Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells. Oncotarget
Lu Y, Lee BH, King RW, et al. (2015) Substrate degradation by the proteasome: a single-molecule kinetic analysis. Science (New York, N.Y.). 348: 1250834
King RW, Finley D. (2014) Sculpting the proteome with small molecules. Nature Chemical Biology. 10: 870-4
Sackton KL, Dimova N, Zeng X, et al. (2014) Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C. Nature. 514: 646-9
Lim HJ, Dimova NV, Tan MK, et al. (2013) The G2/M regulator histone demethylase PHF8 is targeted for degradation by the anaphase-promoting complex containing CDC20. Molecular and Cellular Biology. 33: 4166-80
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