Adrian Salic
Affiliations: | Cell Biology | Harvard Medical School, Boston, MA, United States |
Website:
https://salic.med.harvard.edu/Google:
"Adrian Salic"Parents
Sign in to add mentor| Marc W. Kirschner | grad student | 2000 | Harvard | |
| (Biochemical and developmental studies of the wnt signaling pathway.) | ||||
Children
Sign in to add trainee| Kostadin Ognianov Petrov | grad student | 2011- | Harvard University, Medical School |
| Cindy Y. Jao | grad student | 2011 | Harvard |
| Hanna Tukachinsky | grad student | 2012 | Harvard |
| Lyle V. Lopez | grad student | 2013 | Harvard |
| Daniel Nedelcu | grad student | 2013 | Harvard |
| Bradley M Wierbowski | grad student | 2014-2020 | Harvard Medical School |
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Publications
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| de Almeida Magalhaes T, Liu J, Chan C, et al. (2023) Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens. Developmental Cell |
| Quek RT, Hardy KS, Walker SG, et al. (2023) Screen for Modulation of Nucleocapsid Protein Condensation Identifies Small Molecules with Anti-Coronavirus Activity. Acs Chemical Biology |
| de Almeida Magalhães T, Alencastro Veiga Cruzeiro G, Ribeiro de Sousa G, et al. (2022) Activation of Hedgehog signaling by the oncogenic RELA fusion reveals a primary cilia-dependent vulnerability in Supratentorial Ependymoma. Neuro-Oncology |
| Huang P, Wierbowski BM, Lian T, et al. (2022) Structural basis for catalyzed assembly of the Sonic hedgehog-Patched1 signaling complex. Developmental Cell. 57: 670-685.e8 |
| Liu YC, Wierbowski BM, Salic A. (2022) Hedgehog pathway modulation by glypican 3-conjugated heparan sulfate. Journal of Cell Science |
| Li W, Wang L, Wierbowski BM, et al. (2021) Structural insights into proteolytic activation of the human Dispatched1 transporter for Hedgehog morphogen release. Nature Communications. 12: 6966 |
| Petrov K, de Almeida Magalhaes T, Salic A. (2021) Mechanism and ultrasensitivity in Hedgehog signaling revealed by Patched1 disease mutations. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Wierbowski BM, Petrov K, Aravena L, et al. (2020) Hedgehog Pathway Activation Requires Coreceptor-Catalyzed, Lipid-Dependent Relay of the Sonic Hedgehog Ligand. Developmental Cell |
| Petrov K, Wierbowski BM, Liu J, et al. (2020) Distinct Cation Gradients Power Cholesterol Transport at Different Key Points in the Hedgehog Signaling Pathway. Developmental Cell |
| Magalhães TdA, Cruzeiro GAV, Borges KS, et al. (2020) Abstract A30: Alisertib acts synergistically with sonidegib by modulating primary cilia assembly in a pediatric RELA ependymoma cell line Cancer Research. 80 |