William Wickner

Biochemistry Dartmouth College, Hanover, NH, United States 
"preprotein translocase" from E. coli
"William Wickner"


Cross-listing: Chemistry Tree


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Barbara Conradt grad student UCLA
Teresa Nicolson grad student UCLA (Neurotree)
Pamela A. Silver grad student 1982 UCLA
Li Lily Wang grad student 2003 Dartmouth
Koren A. Nishina grad student 2006 Dartmouth
Kevin M. Collins grad student 2000-2006 Dartmouth Medical School (Neurotree)
Christopher M. Hickey grad student 2010 Dartmouth
Vidya Karunakaran grad student 2014 Dartmouth
Joel M Goodman post-doc UCLA
Roland Lill post-doc UCLA
Gail Mandel post-doc Stanford (Neurotree)
Elmar Schiebel post-doc UCLA
Janet Shaw post-doc UCLA
Christian Ungermann post-doc Dartmouth
Lois Weisman post-doc UCLA
Timothy L. Yahr post-doc Dartmouth-Hitchcock Medical Center (Microtree)
Ross E. Dalbey post-doc 1983-1987 UCLA (Chemistry Tree)
Franz-Ulrich Hartl post-doc 1989-1990 UCLA
Robert A. Arkowitz post-doc 1991-1993 UCLA
Alexey J. Merz post-doc 2000-2004 Dartmouth Medical School
Rutilio A. Fratti post-doc 2002-2006 Dartmouth
Gunnar von Heijne research scientist UCLA
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Jun Y, Wickner W. (2019) Sec17 (α-SNAP) and Sec18 (NSF) restrict membrane fusion to R-SNAREs, Q-SNAREs, and SM proteins from identical compartments. Proceedings of the National Academy of Sciences of the United States of America
Harner M, Wickner W. (2017) Assembly of intermediates for rapid membrane fusion. The Journal of Biological Chemistry
Song H, Orr AS, Duan M, et al. (2017) Sec17/Sec18 act twice, enhancing membrane fusion and then disassembling cis-SNARE complexes. Elife. 6
Orr A, Song H, Rusin SF, et al. (2017) HOPS catalyzes the interdependent assembly of each vacuolar SNARE into a SNARE complex. Molecular Biology of the Cell
Zick M, Wickner W. (2016) Improved reconstitution of yeast vacuole fusion with physiological SNARE concentrations reveals an asymmetric Rab(GTP) requirement. Molecular Biology of the Cell
Baker RW, Jeffrey PD, Zick M, et al. (2015) A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly. Science (New York, N.Y.). 349: 1111-4
Zick M, Stroupe C, Orr A, et al. (2015) Correction: Membranes linked by trans-SNARE complexes require lipids prone to non-bilayer structure for progression to fusion. Elife. 4
Zick M, Orr A, Schwartz ML, et al. (2015) Sec17 can trigger fusion of trans-SNARE paired membranes without Sec18. Proceedings of the National Academy of Sciences of the United States of America. 112: E2290-7
Orr A, Wickner W, Rusin SF, et al. (2015) Yeast vacuolar HOPS, regulated by its kinase, exploits affinities for acidic lipids and Rab:GTP for membrane binding and to catalyze tethering and fusion. Molecular Biology of the Cell. 26: 305-15
Zick M, Wickner WT. (2014) A distinct tethering step is vital for vacuole membrane fusion. Elife. 3: e03251
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