Douglas Elliott Koshland

Johns Hopkins University, Baltimore, MD 
 1987- Carnegie Institution of Washington, Washington, DC, United States 
 2003- Howard Hughes Medical Institute, Chevy Chase, MD, United States 
 2009- University of California, Berkeley, Berkeley, CA 
Genetics, Microbiology Biology, Cell Biology
"Douglas Elliott Koshland"
Koshland, Douglas Elliott A genetic analysis of the secretion of β-lactamase Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Biology, 1982.

Cross-listing: Microtree


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David Botstein grad student 1982 MIT
 (A genetic analysis of the secretion of β-lactamase.)
Leland H. Hartwell post-doc 1982-1986 University of Washington
Marc W. Kirschner post-doc 1986-1987 UCSF


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Dongli Huang grad student 2004 Johns Hopkins (Microtree)
Mark W. Milutinovich grad student 2006 Johns Hopkins (Microtree)
Margaret L. Hoang grad student 2010 Johns Hopkins (Microtree)
Steven D. Calahan grad student 2011 Johns Hopkins (Microtree)
Aaron Z Welch grad student 2012 Johns Hopkins (Microtree)
Lamia Wahba grad student 2013 Johns Hopkins (Microtree)
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Guacci V, Chatterjee F, Robison B, et al. (2019) Communication between distinct subunit interfaces of the cohesin complex promotes its topological entrapment of DNA. Elife. 8
Robison B, Guacci V, Koshland D. (2017) A role for the Smc3 hinge domain in the maintenance of sister chromatid cohesion. Molecular Biology of the Cell
Bloom MS, Koshland D, Guacci V. (2017) Cohesin Function in Cohesion, Condensation and DNA Repair Is Regulated by Wpl1p via a Common Mechanism in Saccharomyces cerevisiae. Genetics
Boothby TC, Tapia H, Brozena AH, et al. (2017) Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation. Molecular Cell. 65: 975-984.e5
Wahba L, Costantino L, Tan FJ, et al. (2016) S1-DRIP-seq identifies high expression and polyA tracts as major contributors to R-loop formation. Genes & Development. 30: 1327-38
Stigler J, Çamdere GÖ, Koshland DE, et al. (2016) Single-Molecule Imaging Reveals a Collapsed Conformational State for DNA-Bound Cohesin. Cell Reports. 15: 988-998
Çamdere G, Guacci V, Stricklin J, et al. (2015) The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering. Elife. 4
Eng T, Guacci V, Koshland D. (2015) Interallelic complementation provides functional evidence for cohesin-cohesin interactions on DNA. Molecular Biology of the Cell. 26: 4224-35
Costantino L, Koshland D. (2015) The Yin and Yang of R-loop biology Current Opinion in Cell Biology. 34: 39-45
Tapia H, Young L, Fox D, et al. (2015) Increasing intracellular trehalose is sufficient to confer desiccation tolerance to Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 112: 6122-7
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