Richard O. Hynes
Affiliations: | Massachusetts Institute of Technology, Cambridge, MA, United States |
Area:
Integrins, Focal AdhesionWebsite:
http://web.mit.edu/hyneslab/Google:
"Richard Hynes"Bio:
Discovered Integrins
https://hynes-lab.mit.edu/people/alumni
Parents
Sign in to add mentor| Paul R. Gross | grad student | MIT | |
| Ian A. MacPherson | post-doc | Imperial Cancer Research Fund |
Children
Sign in to add trainee| Denisa D. Wagner | grad student | 1980 | MIT (Neurotree) |
| Sheila Francis | post-doc | ||
| Eugene E. Marcantonio | post-doc | MIT | |
| Martin A. Schwartz | post-doc | MIT | |
| Jean Schwarzbauer | post-doc | MIT | |
| Donald R. Senger | post-doc | MIT | |
| Lei Xu | post-doc | MIT | |
| Douglas W. DeSimone | post-doc | 1985-1988 | |
| Jun-Lin Guan | post-doc | 1987-1991 | MIT (Chemistry Tree) |
| Peter ST Yuen | research scientist | 2000-2001 | MIT |
BETA: Related publications
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Publications
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| Jailkhani N, Clauser KR, Mak HH, et al. (2023) Proteomic profiling of extracellular matrix components from patient metastases identifies consistently elevated proteins for developing nanobodies that target primary tumors and metastases. Cancer Research |
| Rickelt S, Neyaz A, Condon C, et al. (2021) Agrin loss in Barrett's esophagus-related neoplasia and its utility as a diagnostic and predictive biomarker. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research |
| Benjamin DC, Kang JH, Hamza B, et al. (2020) YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Re-entry into Systemic Circulation. Cancer Research |
| Hebert JD, Tian C, Lamar JM, et al. (2020) The scaffold protein IQGAP1 is crucial for extravasation and metastasis. Scientific Reports. 10: 2439 |
| Tian C, Öhlund D, Rickelt S, et al. (2020) Cancer-cell-derived matrisome proteins promote metastasis in pancreatic ductal adenocarcinoma. Cancer Research |
| Hebert JD, Myers SA, Naba A, et al. (2020) Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches. Cancer Research |
| Tian C, Clauser KR, Öhlund D, et al. (2019) Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells. Proceedings of the National Academy of Sciences of the United States of America |
| Lamar JM, Xiao Y, Norton E, et al. (2018) SRC tyrosine kinase activates the YAP/TAZ axis and thereby drives tumor growth and metastasis. The Journal of Biological Chemistry |
| Chen MB, Hajal C, Benjamin DC, et al. (2018) Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation. Proceedings of the National Academy of Sciences of the United States of America |
| Naba A, Clauser KR, Carr SA, et al. (2018) Abstract 5004: Profiling the extracellular matrix landscape of tumor microenvironments using proteomics Cancer Research. 78: 5004-5004 |