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Richard O. Hynes

Massachusetts Institute of Technology, Cambridge, MA, United States 
Integrins, Focal Adhesion
"Richard Hynes"

Discovered Integrins

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Ragelle H, Naba A, Larson BL, et al. (2017) Comprehensive proteomic characterization of stem cell-derived extracellular matrices. Biomaterials. 128: 147-159
Naba A, Clauser KR, Ding H, et al. (2015) The extracellular matrix: Tools and insights for the "omics" era. Matrix Biology : Journal of the International Society For Matrix Biology
Murphy PA, Begum S, Hynes RO. (2015) Tumor angiogenesis in the absence of fibronectin or its cognate integrin receptors. Plos One. 10: e0120872
Turner CJ, Badu-Nkansah K, Crowley D, et al. (2015) α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo. Development (Cambridge, England). 142: 797-808
Hynes RO. (2014) Stretching the boundaries of extracellular matrix research. Nature Reviews. Molecular Cell Biology. 15: 761-3
Naba A, Clauser KR, Whittaker CA, et al. (2014) Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver. Bmc Cancer. 14: 518
Labelle M, Begum S, Hynes RO. (2014) Platelets guide the formation of early metastatic niches. Proceedings of the National Academy of Sciences of the United States of America. 111: E3053-61
Murphy PA, Hynes RO. (2014) Alternative splicing of endothelial fibronectin is induced by disturbed hemodynamics and protects against hemorrhage of the vessel wall. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2042-50
Turner CJ, Badu-Nkansah K, Crowley D, et al. (2014) Integrin-α5β1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation. Developmental Biology. 392: 381-92
Labelle M, Hynes RO. (2012) The initial hours of metastasis: the importance of cooperative host-tumor cell interactions during hematogenous dissemination. Cancer Discovery. 2: 1091-9
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