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Paul Primakoff

Affiliations: 
Cell Biology and Human Anatomy University of California, Davis, Davis, CA 
Area:
mechanisms involved in sperm-egg fusion and the signaling that initiates mammalian development
Website:
http://www.ucdmc.ucdavis.edu/cellbio/faculty/primakoff/index.html
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"Paul Primakoff"
Cross-listing: Chemistry Tree

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Parents

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Paul Berg grad student 1972 Stanford (Chemistry Tree)
 (The synthesis of transfer ribonucleic acid in Escherichia coli)

Children

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Jennifer Alfieri grad student 2004 UC Davis (Chemistry Tree)
Kathryn K. Stein grad student 2005 UC Davis (Chemistry Tree)

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Publications

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Nishimura H, Gupta S, Myles DG, et al. (2011) Characterization of mouse sperm TMEM190, a small transmembrane protein with the trefoil domain: evidence for co-localization with IZUMO1 and complex formation with other sperm proteins. Reproduction (Cambridge, England). 141: 437-51
Zhu GZ, Gupta S, Myles DG, et al. (2009) Testase 1 (ADAM 24) a sperm surface metalloprotease is required for normal fertility in mice. Molecular Reproduction and Development. 76: 1106-14
Ellerman DA, Pei J, Gupta S, et al. (2009) Izumo is part of a multiprotein family whose members form large complexes on mammalian sperm. Molecular Reproduction and Development. 76: 1188-99
Gupta S, Primakoff P, Myles DG. (2009) Can the presence of wild-type oocytes during insemination rescue the fusion defect of CD9 null oocytes? Molecular Reproduction and Development. 76: 602
He ZY, Gupta S, Myles D, et al. (2009) Loss of surface EWI-2 on CD9 null oocytes. Molecular Reproduction and Development. 76: 629-36
Nishimura H, Myles DG, Primakoff P. (2007) Identification of an ADAM2-ADAM3 complex on the surface of mouse testicular germ cells and cauda epididymal sperm. The Journal of Biological Chemistry. 282: 17900-7
Primakoff P, Myles DG. (2007) Cell-cell membrane fusion during mammalian fertilization. Febs Letters. 581: 2174-80
Runge KE, Evans JE, He ZY, et al. (2007) Oocyte CD9 is enriched on the microvillar membrane and required for normal microvillar shape and distribution. Developmental Biology. 304: 317-25
Stein KK, Go JC, Lane WS, et al. (2006) Proteomic analysis of sperm regions that mediate sperm-egg interactions. Proteomics. 6: 3533-43
Ellerman DA, Myles DG, Primakoff P. (2006) A role for sperm surface protein disulfide isomerase activity in gamete fusion: evidence for the participation of ERp57. Developmental Cell. 10: 831-7
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