Frederick W. Alt, PhD

Affiliations: 
Genetics Harvard University, Cambridge, MA, United States 
Area:
DNA repair, immunology, lymphoma
Website:
https://www.hms.harvard.edu/dms/bbs/fac/Alt.php
Google:
"Frederick W. Alt"
Bio:

https://genetics.hms.harvard.edu/faculty-staff/frederick-w-alt
https://www.hhmi.org/scientists/frederick-w-alt
http://searchworks.stanford.edu/view/761131

Cross-listing: Neurotree - Chemistry Tree

Parents

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Robert T. Schimke grad student 1977 Stanford (Chemistry Tree)
 (The molecular mechanism of dihydrofolate reductase overproduction in methotrexate-resistant variants of culture murine cells)
David Baltimore post-doc 1982 MIT

Children

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George Yancopoulos grad student Columbia University Medical School (Neurotree)
Yang Xu grad student 1994 Harvard (Stem Cell Tree)
Darryll D. Dudley grad student 2003 Harvard (Neurotree)
Sean E. Rooney grad student 2003 Harvard (Neurotree)
David H. Jung grad student 2006 Harvard (Neurotree)
Cristian Boboila grad student 2005-2011 Harvard (Neurotree)
Tingting Zhang-Kharas grad student 2005-2011 Harvard (Chemistry Tree)
Suprawee Tepsuporn grad student 2013 Harvard (Neurotree)
Uttiya Basu post-doc Harvard
Jayanta Chaudhuri post-doc (MathTree)
Huan Chen post-doc Harvard
Bjoern Schwer post-doc (Neurotree)
Adam Yongxin Ye post-doc 2018- Harvard Medical School (GenetiTree)
Ronald A. DePinho post-doc 1984-1988 Columbia (Telomere and Telomerase Tree)
Angela K. Eggleston post-doc 1999-1999 Harvard Medical School - Boston Children's Hospital (Chemistry Tree)
Shan Zha post-doc 2004-2009 Harvard - Boston Children's Hospital (Chemistry Tree)
Richard L Frock post-doc 2010-2017 Harvard Medical School - Boston Children's Hospital
BETA: Related publications

Publications

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Zhang Y, Zhang X, Dai HQ, et al. (2022) The role of chromatin loop extrusion in antibody diversification. Nature Reviews. Immunology
Wang Y, Wang M, Djekidel MN, et al. (2021) eccDNAs are apoptotic products with high innate immunostimulatory activity. Nature. 599: 308-314
Cheng YC, Snavely A, Barrett LB, et al. (2021) Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons. Cell Reports. 36: 109666
Liang Z, Kumar V, Le Bouteiller M, et al. (2021) Ku70 suppresses alternative end joining in G1-arrested progenitor B cells. Proceedings of the National Academy of Sciences of the United States of America. 118
Dai HQ, Hu H, Lou J, et al. (2021) Loop extrusion mediates physiological Igh locus contraction for RAG scanning. Nature
Dai HQ, Liang Z, Chang AN, et al. (2020) Direct analysis of brain phenotypes via neural blastocyst complementation. Nature Protocols
Ba Z, Lou J, Ye AY, et al. (2020) CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning. Nature
Chen H, Zhang Y, Ye AY, et al. (2020) BCR selection and affinity maturation in Peyer's patch germinal centres. Nature
Tian M, McGovern K, Cheng HL, et al. (2020) Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models. Proceedings of the National Academy of Sciences of the United States of America
Bradley T, Kuraoka M, Yeh CH, et al. (2020) Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948
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