Frederick W. Alt, PhD
Affiliations: | Genetics | Harvard University, Cambridge, MA, United States |
Area:
DNA repair, immunology, lymphomaWebsite:
https://www.hms.harvard.edu/dms/bbs/fac/Alt.phpGoogle:
"Frederick W. Alt"Bio:
https://genetics.hms.harvard.edu/faculty-staff/frederick-w-alt
https://www.hhmi.org/scientists/frederick-w-alt
http://searchworks.stanford.edu/view/761131
Cross-listing: Neurotree - Chemistry Tree
Parents
Sign in to add mentor| Robert T. Schimke | grad student | 1977 | Stanford (Chemistry Tree) | |
| (The molecular mechanism of dihydrofolate reductase overproduction in methotrexate-resistant variants of culture murine cells) | ||||
| David Baltimore | post-doc | 1982 | MIT | |
Children
Sign in to add trainee| George Yancopoulos | grad student | Columbia University Medical School (Neurotree) | |
| Yang Xu | grad student | 1994 | Harvard (Stem Cell Tree) |
| Darryll D. Dudley | grad student | 2003 | Harvard (Neurotree) |
| Sean E. Rooney | grad student | 2003 | Harvard (Neurotree) |
| David H. Jung | grad student | 2006 | Harvard (Neurotree) |
| Cristian Boboila | grad student | 2005-2011 | Harvard (Neurotree) |
| Tingting Zhang-Kharas | grad student | 2005-2011 | Harvard (Chemistry Tree) |
| Suprawee Tepsuporn | grad student | 2013 | Harvard (Neurotree) |
| Uttiya Basu | post-doc | Harvard | |
| Jayanta Chaudhuri | post-doc | (MathTree) | |
| Huan Chen | post-doc | Harvard | |
| Bjoern Schwer | post-doc | (Neurotree) | |
| Adam Yongxin Ye | post-doc | 2018- | Harvard Medical School (GenetiTree) |
| Ronald A. DePinho | post-doc | 1984-1988 | Columbia (Telomere and Telomerase Tree) |
| Angela K. Eggleston | post-doc | 1999-1999 | Harvard Medical School - Boston Children's Hospital (Chemistry Tree) |
| Shan Zha | post-doc | 2004-2009 | Harvard - Boston Children's Hospital (Chemistry Tree) |
| Richard L Frock | post-doc | 2010-2017 | Harvard Medical School - Boston Children's Hospital |
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Publications
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| Zhang Y, Zhang X, Dai HQ, et al. (2022) The role of chromatin loop extrusion in antibody diversification. Nature Reviews. Immunology |
| Wang Y, Wang M, Djekidel MN, et al. (2021) eccDNAs are apoptotic products with high innate immunostimulatory activity. Nature. 599: 308-314 |
| Cheng YC, Snavely A, Barrett LB, et al. (2021) Topoisomerase I inhibition and peripheral nerve injury induce DNA breaks and ATF3-associated axon regeneration in sensory neurons. Cell Reports. 36: 109666 |
| Liang Z, Kumar V, Le Bouteiller M, et al. (2021) Ku70 suppresses alternative end joining in G1-arrested progenitor B cells. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Dai HQ, Hu H, Lou J, et al. (2021) Loop extrusion mediates physiological Igh locus contraction for RAG scanning. Nature |
| Dai HQ, Liang Z, Chang AN, et al. (2020) Direct analysis of brain phenotypes via neural blastocyst complementation. Nature Protocols |
| Ba Z, Lou J, Ye AY, et al. (2020) CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning. Nature |
| Chen H, Zhang Y, Ye AY, et al. (2020) BCR selection and affinity maturation in Peyer's patch germinal centres. Nature |
| Tian M, McGovern K, Cheng HL, et al. (2020) Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models. Proceedings of the National Academy of Sciences of the United States of America |
| Bradley T, Kuraoka M, Yeh CH, et al. (2020) Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948 |