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Tom Maniatis, Phd

Affiliations: 
Biochemistry and Molecular Biophysics Harvard University, Cambridge, MA, United States 
 Columbia University, New York, NY 
Area:
Regulation of RNA Transcription and Splicing, The Role of Neuroinflammation in ALS, Neurobiology of Disease, Synapses and Circuits, Stem Cell Biology, ALS Disease Mechanisms, Genetic Basis of Neurological Diseases
Website:
http://biochemistry.hs.columbia.edu/faculty/maniatis.htm
Google:
"Tom Maniatis"
Bio:

http://www.nasonline.org/member-directory/members/45746.html
http://www.maniatislab.columbia.edu/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461937/
http://en.wikipedia.org/wiki/Tom_Maniatis

Cross-listing: FlyTree - Chemistry Tree - Neurotree

Parents

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Leonard S. Lerman grad student 1971 Vanderbilt (Chemistry Tree)
 (The structure of DNA after phase separation from aqueous polymer solutions)
Mark Ptashne post-doc Harvard (Chemistry Tree)
Frederick Sanger post-doc MRC-LMB (Chemistry Tree)

Children

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Michelle C. Siao research assistant 2005-2010 Harvard (Neurotree)
Victoria Lynn Corbin grad student (FlyTree)
Adrian R. Krainer grad student Harvard (Neurotree)
Kristen Lynch grad student Penn (Neurotree)
Robin Reed grad student Harvard
Kai Zinn grad student (FlyTree)
Brian Seed grad student 1981 Caltech (Chemistry Tree)
Ted Abel grad student 1987-1993 Harvard (Neurotree)
Bing Ren grad student 1998 Harvard (Chemistry Tree)
Christopher P. Sears grad student 2001 Harvard (FlyTree)
Zhaolan Zhou grad student 2001 Harvard (FlyTree)
Chih-Hsuan Lin grad student 2002 Harvard (FlyTree)
Tae Hoon Kim grad student 1996-2002 Harvard (Chemistry Tree)
Rui Zhou grad student 2003 Harvard (FlyTree)
Shuning Liao grad student 2004 Harvard
Bosiljka Tasic grad student 2004 Harvard (Neurotree)
Scott A. Ribich grad student 2005 Harvard (FlyTree)
Sean M. Buchanan grad student 2009 Harvard (FlyTree)
Sze-Ling Ng grad student 2010 Harvard (FlyTree)
Kevin G. Monahan grad student 2011 Harvard (FlyTree)
Emiko T. Morimoto grad student 2012 Harvard (FlyTree)
Hubert Amrein post-doc (Neurotree)
Patrick Charnay post-doc Harvard (Neurotree)
Alan Michelson post-doc Harvard (FlyTree)
Jim Posakony post-doc Harvard (FlyTree)
Nicholas Proudfoot post-doc CSHL (Chemistry Tree)
Gary Struhl post-doc Harvard University, Columbia University (FlyTree)
Weisheng Victor Chen post-doc 2009- Columbia (Neurotree)
Lydia Villa-Komaroff post-doc 1976 Harvard
Ross C. Hardison post-doc 1977-1980 Caltech
Daniel C. DiMaio post-doc 1981-1983 Harvard (Chemistry Tree)
Richard Morris Myers post-doc 1982-1985 Harvard (Neurotree)
Xiang-Dong Fu post-doc 1990-1992 Harvard (Chemistry Tree)
Jane Ying Wu post-doc 1992-1997 Harvard (Neurotree)
Brenton R. Graveley post-doc 1996-1999 Harvard (FlyTree)
Qiang Wu post-doc 1998-2001 (Neurotree)
Isaac Chiu post-doc 2009-2010 MCB Harvard University (Neurotree)
Hemali P. Phatnani post-doc 2006-2013 Columbia (Chemistry Tree)
BETA: Related publications

Publications

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Harding O, Evans CS, Ye J, et al. (2021) ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy. Proceedings of the National Academy of Sciences of the United States of America. 118
Lencz T, Yu J, Khan RR, et al. (2021) Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia. Neuron
Zhang Q, Bastard P, Liu Z, et al. (2020) Inborn errors of type I IFN immunity in patients with life-threatening COVID-19. Science (New York, N.Y.)
Flaherty E, Maniatis T. (2020) The role of clustered protocadherins in neurodevelopment and neuropsychiatric diseases. Current Opinion in Genetics & Development. 65: 144-150
Mancia Leon WR, Spatazza J, Rakela B, et al. (2020) Clustered gamma-protocadherins regulate cortical interneuron programmed cell death. Elife. 9
Gerbino V, Kaunga E, Ye J, et al. (2020) The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice. Neuron
Leon WRM, Spatazza J, Rakela B, et al. (2020) Author response: Clustered gamma-protocadherins regulate cortical interneuron programmed cell death Elife
Ye J, Cheung J, Gerbino V, et al. (2019) Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity. Proceedings of the National Academy of Sciences of the United States of America
Canzio D, Maniatis T. (2019) The generation of a protocadherin cell-surface recognition code for neural circuit assembly. Current Opinion in Neurobiology. 59: 213-220
Brasch J, Goodman KM, Noble AJ, et al. (2019) Visualization of clustered protocadherin neuronal self-recognition complexes. Nature
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